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2-Methoxyestradiol-3,17-O,O-bis-sulfamate inhibits store-operated Ca2+ entry in T lymphocytes and prevents experimental autoimmune encephalomyelitis.
Hosang, Leon; Löhndorf, Anke; Dohle, Wolfgang; Rosche, Anette; Marry, Stephen; Diercks, Björn-Philipp; Müller-Kirschbaum, Lukas C; Flügel, Lioba T; Potter, Barry V L; Odoardi, Francesca; Guse, Andreas H; Flügel, Alexander.
Afiliación
  • Hosang L; Institute for Neuroimmunology and Multiple Sclerosis Research, University Medical Center Göttingen, Von-Siebold-Straße 3a, D-37075 Göttingen, Germany.
  • Löhndorf A; The Calcium Signalling Group, Department of Biochemistry and Molecular Cell Biology, University Medical Center Hamburg-Eppendorf, Martinistraße 52, D-20246 Hamburg, Germany.
  • Dohle W; Drug Discovery & Medicinal Chemistry, Department of Pharmacology, University of Oxford, Mansfield Road, Oxford OX1 3QT, United Kingdom.
  • Rosche A; The Calcium Signalling Group, Department of Biochemistry and Molecular Cell Biology, University Medical Center Hamburg-Eppendorf, Martinistraße 52, D-20246 Hamburg, Germany.
  • Marry S; Institute for Neuroimmunology and Multiple Sclerosis Research, University Medical Center Göttingen, Von-Siebold-Straße 3a, D-37075 Göttingen, Germany.
  • Diercks BP; The Calcium Signalling Group, Department of Biochemistry and Molecular Cell Biology, University Medical Center Hamburg-Eppendorf, Martinistraße 52, D-20246 Hamburg, Germany.
  • Müller-Kirschbaum LC; Institute for Neuroimmunology and Multiple Sclerosis Research, University Medical Center Göttingen, Von-Siebold-Straße 3a, D-37075 Göttingen, Germany.
  • Flügel LT; Institute for Neuroimmunology and Multiple Sclerosis Research, University Medical Center Göttingen, Von-Siebold-Straße 3a, D-37075 Göttingen, Germany; Department of Neurology, University Medical Center Göttingen, Robert-Koch-Straße 40, D-37075 Göttingen, Germany.
  • Potter BVL; Drug Discovery & Medicinal Chemistry, Department of Pharmacology, University of Oxford, Mansfield Road, Oxford OX1 3QT, United Kingdom.
  • Odoardi F; Institute for Neuroimmunology and Multiple Sclerosis Research, University Medical Center Göttingen, Von-Siebold-Straße 3a, D-37075 Göttingen, Germany.
  • Guse AH; The Calcium Signalling Group, Department of Biochemistry and Molecular Cell Biology, University Medical Center Hamburg-Eppendorf, Martinistraße 52, D-20246 Hamburg, Germany. Electronic address: guse@uke.de.
  • Flügel A; Institute for Neuroimmunology and Multiple Sclerosis Research, University Medical Center Göttingen, Von-Siebold-Straße 3a, D-37075 Göttingen, Germany. Electronic address: fluegel@med.uni-goettingen.de.
Biochim Biophys Acta Mol Cell Res ; 1870(6): 119485, 2023 08.
Article en En | MEDLINE | ID: mdl-37150482
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Linfocitos T / Encefalomielitis Autoinmune Experimental Tipo de estudio: Prognostic_studies Límite: Animals Idioma: En Revista: Biochim Biophys Acta Mol Cell Res Año: 2023 Tipo del documento: Article País de afiliación: Alemania Pais de publicación: Países Bajos
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Linfocitos T / Encefalomielitis Autoinmune Experimental Tipo de estudio: Prognostic_studies Límite: Animals Idioma: En Revista: Biochim Biophys Acta Mol Cell Res Año: 2023 Tipo del documento: Article País de afiliación: Alemania Pais de publicación: Países Bajos