Fosmanogepix Therapy of Disseminated Fusarium Infection.

Winston, Drew J; Young, Patricia A; Schlamm, Haran T; Schiller, Gary J

Winston, Drew J; Young, Patricia A; Schlamm, Haran T; Schiller, Gary J.

Afiliación

Winston DJ; Division of Hematology-Oncology, Department of Medicine, Center for Health Sciences, University of California, Los Angeles, USA.
Young PA; Division of Hematology-Oncology, Department of Medicine, Center for Health Sciences, University of California, Los Angeles, USA.
Schlamm HT; HTS Pharma Consulting, San Diego, California, USA.
Schiller GJ; Division of Hematology-Oncology, Department of Medicine, Center for Health Sciences, University of California, Los Angeles, USA.

Clin Infect Dis ; 77(6): 848-850, 2023 09 18.

Article en En | MEDLINE | ID: mdl-37220752

ABSTRACT

ABSTRACT

Invasive Fusarium infections cause high mortality. Fosmanogepix, a first-in-class antifungal agent, has potent activity against Fusarium. A patient with acute leukemia with invasive fusariosis, probably involving the central nervous system and caused by Fusarium lactis resistant to currently available antifungal agents, was cured of her infection with fosmanogepix. Fosmanogepix was well tolerated.

Asunto(s)

Fusariosis; Leucemia Mieloide Aguda; Humanos; Femenino; Antifúngicos/uso terapéutico; Fusariosis/tratamiento farmacológico; Fusariosis/microbiología; Leucemia Mieloide Aguda/tratamiento farmacológico; Sistema Nervioso Central

Palabras clave

Fusarium infection; fosmanogepix

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Leucemia Mieloide Aguda / Fusariosis Límite: Female / Humans Idioma: En Revista: Clin Infect Dis Asunto de la revista: DOENCAS TRANSMISSIVEIS Año: 2023 Tipo del documento: Article País de afiliación: Estados Unidos

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