Investigation of heteroscedasticity in polygenic risk scores across 15 quantitative traits.

Jung, Hyein; Jung, Hae-Un; Baek, Eun Ju; Chung, Ju Yeon; Kwon, Shin Young; Kang, Ji-One; Lim, Ji Eun; Oh, Bermseok

Jung, Hyein; Jung, Hae-Un; Baek, Eun Ju; Chung, Ju Yeon; Kwon, Shin Young; Kang, Ji-One; Lim, Ji Eun; Oh, Bermseok.

Afiliación

Jung H; Department of Biomedical Science, Graduate School, Kyung Hee University, Seoul, Republic of Korea.
Jung HU; Department of Biomedical Science, Graduate School, Kyung Hee University, Seoul, Republic of Korea.
Baek EJ; Mendel, Seoul, Republic of Korea.
Chung JY; Department of Biomedical Science, Graduate School, Kyung Hee University, Seoul, Republic of Korea.
Kwon SY; Department of Biomedical Science, Graduate School, Kyung Hee University, Seoul, Republic of Korea.
Kang JO; Department of Biochemistry and Molecular Biology, School of Medicine, Kyung Hee University, Seoul, Republic of Korea.
Lim JE; Department of Biochemistry and Molecular Biology, School of Medicine, Kyung Hee University, Seoul, Republic of Korea.
Oh B; Department of Biomedical Science, Graduate School, Kyung Hee University, Seoul, Republic of Korea.

Front Genet ; 14: 1150889, 2023.

Article en En | MEDLINE | ID: mdl-37229196

Palabras clave

heteroscedasticity; linear regression model; polygenic risk score (PRS); prediction accuracy; quantitative trait

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Tipo de estudio: Etiology_studies / Prognostic_studies / Risk_factors_studies Idioma: En Revista: Front Genet Año: 2023 Tipo del documento: Article Pais de publicación: Suiza

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