Chloramphenicol Derivatization in Its Primary Hydroxyl Group with Basic Amino Acids Leads to New Pharmacophores with High Antimicrobial Activity.

Tsirogianni, Artemis; Kournoutou, Georgia G; Mpogiatzoglou, Maria; Dinos, George; Athanassopoulos, Constantinos M

Tsirogianni, Artemis; Kournoutou, Georgia G; Mpogiatzoglou, Maria; Dinos, George; Athanassopoulos, Constantinos M.

Afiliación

Tsirogianni A; Synthetic Organic Chemistry Laboratory, Department of Chemistry, University of Patras, GR-26504 Patras, Greece.
Kournoutou GG; Department of Biochemistry, School of Medicine, University of Patras, GR-26504 Patras, Greece.
Mpogiatzoglou M; Department of Biochemistry, School of Medicine, University of Patras, GR-26504 Patras, Greece.
Dinos G; Department of Biochemistry, School of Medicine, University of Patras, GR-26504 Patras, Greece.
Athanassopoulos CM; Synthetic Organic Chemistry Laboratory, Department of Chemistry, University of Patras, GR-26504 Patras, Greece.

Antibiotics (Basel) ; 12(5)2023 Apr 29.

Article en En | MEDLINE | ID: mdl-37237735

Palabras clave

antibiotic resistance; antibiotics; chloramphenicol; peptidyl transferase; ribosome

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Antibiotics (Basel) Año: 2023 Tipo del documento: Article País de afiliación: Grecia Pais de publicación: Suiza

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