Evaluation of the Aptima BV and CV/TV assays compared to conventional laboratory based testing methods for the diagnosis of vaginitis.
Diagn Microbiol Infect Dis
; 106(4): 115953, 2023 Aug.
Article
en En
| MEDLINE
| ID: mdl-37295185
ABSTRACT
PURPOSE:
Vaginitis is caused by bacterial vaginosis (BV), Candida vaginitis (CV) and Trichomonas vaginalis (TV). This retrospective study evaluates the performance of the Aptima CV/TV, and BV assays on the automated Panther system.METHODS:
Two hundred forty-two multitest swabs were tested on the CV/TV assay and 422 on the BV assay. Positive and negative percent agreement (PPA, NPA) of the Candida glabrata (CG), Candida species group (CSG), TV and BV targets were calculated using a modified gold standard, with review of Gram smear and the usage of the Allplex Vaginitis Screening Assay to resolve discrepancies.RESULTS:
The PPA and NPA were respectively 98.4% and 95.9% for BV, 100% and 95.4% for CSG, 100% and 99% for CG, and 100% and 100% for TV, and when compared to consensus results.CONCLUSION:
The CV/TV and BV assays surpassed the acceptance criteria threshold of 95%, and proved to be an excellent alternative to conventional testing.Palabras clave
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Trichomonas vaginalis
/
Vaginitis por Trichomonas
/
Candidiasis Vulvovaginal
/
Vaginosis Bacteriana
Tipo de estudio:
Diagnostic_studies
/
Observational_studies
Límite:
Female
/
Humans
Idioma:
En
Revista:
Diagn Microbiol Infect Dis
Año:
2023
Tipo del documento:
Article