Enhancing Tobacco Quitline Outcomes for African American Adults: An RCT of a Culturally Specific Intervention.

INTRODUCTION: This study tested the effectiveness of a culturally specific tobacco cessation video intervention among African American quitline enrollees. STUDY DESIGN: This was a 3-arm semipragmatic RCT. SETTING/PARTICIPANTS: African American adults (N=1,053) were recruited from the North Carolina tobacco quitline and data were collected between 2017 and 2020. INTERVENTION: Participants were randomized to receive (1) quitline services only; (2) quitline services plus a standard, general audience video intervention; or (3) quitline services plus Pathways to Freedom (PTF), a culturally specific video intervention designed to promote cessation among African American persons. MAIN OUTCOME MEASURES: The primary outcome was self-reported 7-day point prevalence smoking abstinence at 6 months. Secondary outcomes included 7-day and 24-hour point prevalence abstinence at 3 months, 28-day continuous abstinence, and intervention engagement. Data analyses occurred in 2020 and 2022. RESULTS: At 6 months, 7-day point prevalence abstinence was significantly greater in the Pathways to Freedom Video arm compared with quitline-only (OR=1.5, CI=1.11, 2.07). Twenty four-hour point prevalence abstinence was significantly greater in the Pathways to Freedom (than in quitline-only) group at 3 (OR=1.49, 95% CI=1.03, 2.15) and 6 (OR=1.58, 95% CI=1.10, 2.28) months. At 6 months, 28-day continuous abstinence (OR=1.60, 95% CI=1.17, 2.20) was significantly greater in the Pathways to Freedom Video arm than in the quitline-only arm. Views of the Pathways to Freedom Video were 76% higher than views of the standard video. CONCLUSIONS: Culturally specific tobacco interventions delivered through state quitlines can increase cessation and thus have the potential to decrease health disparities among African American adults. TRIAL REGISTRATION: This study is registered at www. CLINICALTRIALS: gov NCT03064971.