Novel organoboron complexes with robust core: Synthesis, functionalization, and subcellular targeting.
Bioorg Chem
; 138: 106662, 2023 09.
Article
en En
| MEDLINE
| ID: mdl-37307714
ABSTRACT
The construction of novel organoboron complexes with facile synthesis and unique advantages for biological imaging remains a challenge and thus has garnered considerable attention. Herein, we developed a new molecular platform, boron indolin-3-one-pyrrol (BOIN3OPY) via a two-step sequential reaction. The molecular core is robust enough to allow for post-functionalization to produce versatile dyes. When compared to the standard BODIPY, these dyes feature an N,O-bidentate seven-membered ring center, significantly redshifted absorption, and a larger Stokes shift. This study establishes a new molecular platform that provides more flexibility for the functional regulation of dyes.
Palabras clave
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1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Compuestos de Boro
/
Colorantes Fluorescentes
Idioma:
En
Revista:
Bioorg Chem
Año:
2023
Tipo del documento:
Article