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An improved reporter identifies ruxolitinib as a potent and cardioprotective CaMKII inhibitor.
Reyes Gaido, Oscar E; Pavlaki, Nikoleta; Granger, Jonathan M; Mesubi, Olurotimi O; Liu, Bian; Lin, Brian L; Long, Alan; Walker, David; Mayourian, Joshua; Schole, Kate L; Terrillion, Chantelle E; Nkashama, Lubika J; Hulsurkar, Mohit M; Dorn, Lauren E; Ferrero, Kimberly M; Huganir, Richard L; Müller, Frank U; Wehrens, Xander H T; Liu, Jun O; Luczak, Elizabeth D; Bezzerides, Vassilios J; Anderson, Mark E.
Afiliación
  • Reyes Gaido OE; Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA.
  • Pavlaki N; Department of Cardiology, Boston Children's Hospital and Harvard Medical School, Boston, MA 02115, USA.
  • Granger JM; Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA.
  • Mesubi OO; Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA.
  • Liu B; Solomon H. Snyder Department of Neuroscience, Johns Hopkins School of Medicine, Baltimore, MD 21205, USA.
  • Lin BL; Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA.
  • Long A; Department of Pharmacology and Molecular Sciences, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA.
  • Walker D; Department of Cardiology, Boston Children's Hospital and Harvard Medical School, Boston, MA 02115, USA.
  • Mayourian J; Department of Cardiology, Boston Children's Hospital and Harvard Medical School, Boston, MA 02115, USA.
  • Schole KL; Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA.
  • Terrillion CE; Department of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA.
  • Nkashama LJ; Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA.
  • Hulsurkar MM; Cardiovascular Research Institute and Department of Integrative Physiology, Baylor College of Medicine, Houston, TX 77030, USA.
  • Dorn LE; Cardiovascular Research Institute and Department of Integrative Physiology, Baylor College of Medicine, Houston, TX 77030, USA.
  • Ferrero KM; Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA.
  • Huganir RL; Solomon H. Snyder Department of Neuroscience, Johns Hopkins School of Medicine, Baltimore, MD 21205, USA.
  • Müller FU; Institute of Pharmacology and Toxicology, University of Münster, Münster 48149, Germany.
  • Wehrens XHT; Cardiovascular Research Institute and Department of Integrative Physiology, Baylor College of Medicine, Houston, TX 77030, USA.
  • Liu JO; Departments of Medicine, Neuroscience, and Pediatrics, Center for Space Medicine, Baylor College of Medicine, Houston, TX 77030, USA.
  • Luczak ED; Department of Pharmacology and Molecular Sciences, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA.
  • Bezzerides VJ; Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA.
  • Anderson ME; Department of Cardiology, Boston Children's Hospital and Harvard Medical School, Boston, MA 02115, USA.
Sci Transl Med ; 15(701): eabq7839, 2023 06 21.
Article en En | MEDLINE | ID: mdl-37343080
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Proteína Quinasa Tipo 2 Dependiente de Calcio Calmodulina / Cardiopatías Tipo de estudio: Prognostic_studies Límite: Animals / Child / Humans Idioma: En Revista: Sci Transl Med Asunto de la revista: CIENCIA / MEDICINA Año: 2023 Tipo del documento: Article País de afiliación: Estados Unidos
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Proteína Quinasa Tipo 2 Dependiente de Calcio Calmodulina / Cardiopatías Tipo de estudio: Prognostic_studies Límite: Animals / Child / Humans Idioma: En Revista: Sci Transl Med Asunto de la revista: CIENCIA / MEDICINA Año: 2023 Tipo del documento: Article País de afiliación: Estados Unidos