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Value of Myocardial Contrast Echocardiography in Detecting Coronary Microcirculatory Dysfunction in Ischemia With Non-obstructive Coronary Artery Disease.
Zhang, Jianqiang; Guan, Lina; Li, Xiaohong; Yang, Yuanyuan; Ma, Yuexia; Mu, Yuming.
Afiliación
  • Zhang J; Department of Echocardiography, First Affiliated Hospital of Xinjiang Medical University, Urumqi, Xinjiang, China; Xinjiang Key Laboratory of Ultrasound Medicine, Urumqi, Xinjiang, China.
  • Guan L; Department of Echocardiography, First Affiliated Hospital of Xinjiang Medical University, Urumqi, Xinjiang, China; Xinjiang Key Laboratory of Ultrasound Medicine, Urumqi, Xinjiang, China.
  • Li X; Department of Echocardiography, First Affiliated Hospital of Xinjiang Medical University, Urumqi, Xinjiang, China.
  • Yang Y; Department of Echocardiography, First Affiliated Hospital of Xinjiang Medical University, Urumqi, Xinjiang, China; Xinjiang Key Laboratory of Ultrasound Medicine, Urumqi, Xinjiang, China.
  • Ma Y; Department of Echocardiography, First Affiliated Hospital of Xinjiang Medical University, Urumqi, Xinjiang, China; Xinjiang Key Laboratory of Ultrasound Medicine, Urumqi, Xinjiang, China.
  • Mu Y; Department of Echocardiography, First Affiliated Hospital of Xinjiang Medical University, Urumqi, Xinjiang, China; Xinjiang Key Laboratory of Ultrasound Medicine, Urumqi, Xinjiang, China. Electronic address: mym1234@126.com.
Ultrasound Med Biol ; 49(9): 2089-2094, 2023 09.
Article en En | MEDLINE | ID: mdl-37344240
ABSTRACT

OBJECTIVE:

The aim of this study was to evaluate the value of myocardial contrast echocardiography (MCE) in detecting coronary microcirculation function dysfunction in ischemia with non-obstructive coronary artery (INOCA) disease.

METHODS:

Twenty-one patients with a clinical diagnosis of INOCA were admitted to the First Affiliated Hospital of Xinjiang Medical University because of chest pain. All participants underwent MCE and [18F]fluorodeoxyglucose (FDG) positron emission tomography/computed tomography myocardial metabolic imaging. With the results of FDG PET taken as the gold standard, all myocardial segments were divided into a normal control group and a coronary artery microcirculation dysfunction (CMCD) group. We used MCE to measure myocardial perfusion parameters, including the ascending slope (ß), time to peak (TTP), A and A × ß. The receiver operating characteristic (ROC) curves of ß, TTP, A and A × ß were calculated to evaluate the diagnostic value of MCE for CMCD.

RESULTS:

A total of 122 and 218 segments were investigated in the CMCD and control groups, respectively. On the basis of the statistical analysis of the MCE parameters of the two groups, the myocardial perfusion parameters ß, A and A × ß of all segments in the CMCD group decreased, and the TTP in the basal segment of the CMCD group was longer than that of the normal control group (all p values <0.05). On the basis of analysis of the ROC curve, ß had the highest diagnostic efficiency in the middle segment.

CONCLUSION:

This study found that MCE is valuable in the diagnosis of non-obstructive coronary artery complicated by CMCD.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Enfermedad de la Arteria Coronaria Tipo de estudio: Diagnostic_studies / Prognostic_studies Aspecto: Patient_preference Límite: Humans Idioma: En Revista: Ultrasound Med Biol Año: 2023 Tipo del documento: Article País de afiliación: China

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Enfermedad de la Arteria Coronaria Tipo de estudio: Diagnostic_studies / Prognostic_studies Aspecto: Patient_preference Límite: Humans Idioma: En Revista: Ultrasound Med Biol Año: 2023 Tipo del documento: Article País de afiliación: China