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SMA-TB: study protocol for the phase 2b randomized double-blind, placebo-controlled trial to estimate the potential efficacy and safety of two repurposed drugs, acetylsalicylic acid and ibuprofen, for use as adjunct therapy added to, and compared with, the standard WHO recommended TB regimen.
Arias, Lilibeth; Otwombe, Kennedy; Waja, Ziyaad; Tukvadze, Nestani; Korinteli, Tamta; Moloantoa, Tumelo; Fonseca, Kaori L; Pillay, Natasha; Seiphetlo, Thabiso; Ouchi-Vernet, Dan; Siles, Adrian; Carabias, Lidia; Quiñones, Carles; Vashakidze, Sergo; Martinson, Neil; Vilaplana, Cristina.
Afiliación
  • Arias L; Unitat de Tuberculosi Experimental, Germans Trias I Pujol Research Institute (IGTP), Badalona, Catalonia, Spain.
  • Otwombe K; Centro de Investigación Biomédica en Red de Enfermedades Respiratorias (CIBERES), Madrid, Spain.
  • Waja Z; Perinatal HIV Research Unit (PHRU), University of the Witwatersrand, Johannesburg, South Africa.
  • Tukvadze N; Perinatal HIV Research Unit (PHRU), University of the Witwatersrand, Johannesburg, South Africa.
  • Korinteli T; National Center for Tuberculosis and Lung Diseases (NCTLD), Tbilisi, Georgia.
  • Moloantoa T; National Center for Tuberculosis and Lung Diseases (NCTLD), Tbilisi, Georgia.
  • Fonseca KL; Perinatal HIV Research Unit (PHRU), University of the Witwatersrand, Johannesburg, South Africa.
  • Pillay N; Unitat de Tuberculosi Experimental, Germans Trias I Pujol Research Institute (IGTP), Badalona, Catalonia, Spain.
  • Seiphetlo T; Centro de Investigación Biomédica en Red de Enfermedades Respiratorias (CIBERES), Madrid, Spain.
  • Ouchi-Vernet D; Perinatal HIV Research Unit (PHRU), University of the Witwatersrand, Johannesburg, South Africa.
  • Siles A; Perinatal HIV Research Unit (PHRU), University of the Witwatersrand, Johannesburg, South Africa.
  • Carabias L; Institut d'Investigació en Atenció Primària de Salut Jordi Gol (IDIAPJgol), Barcelona, Spain.
  • Quiñones C; Pharmacy department, Germans Trias I Pujol Hospital and Research Institute (HUGTIP-IGTP), Badalona, Catalonia, Spain.
  • Vashakidze S; Pharmacy department, Germans Trias I Pujol Hospital and Research Institute (HUGTIP-IGTP), Badalona, Catalonia, Spain.
  • Martinson N; Pharmacy department, Germans Trias I Pujol Hospital and Research Institute (HUGTIP-IGTP), Badalona, Catalonia, Spain.
  • Vilaplana C; National Center for Tuberculosis and Lung Diseases (NCTLD), Tbilisi, Georgia.
Trials ; 24(1): 435, 2023 Jun 28.
Article en En | MEDLINE | ID: mdl-37370174
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Tuberculosis Pulmonar / Mycobacterium tuberculosis Tipo de estudio: Clinical_trials / Diagnostic_studies / Guideline / Prognostic_studies Límite: Adult / Humans Idioma: En Revista: Trials Asunto de la revista: MEDICINA / TERAPEUTICA Año: 2023 Tipo del documento: Article País de afiliación: España Pais de publicación: Reino Unido
Texto completo
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Imprimir
XML
PubMed Links
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Tuberculosis Pulmonar / Mycobacterium tuberculosis Tipo de estudio: Clinical_trials / Diagnostic_studies / Guideline / Prognostic_studies Límite: Adult / Humans Idioma: En Revista: Trials Asunto de la revista: MEDICINA / TERAPEUTICA Año: 2023 Tipo del documento: Article País de afiliación: España Pais de publicación: Reino Unido