Chronic social defeat alters brain vascular-associated cell gene expression patterns leading to vascular dysfunction and immune system activation.

Samuels, Joshua D; Lotstein, Madison L; Lehmann, Michael L; Elkahloun, Abdel G; Banerjee, Subhadra; Herkenham, Miles

Samuels, Joshua D; Lotstein, Madison L; Lehmann, Michael L; Elkahloun, Abdel G; Banerjee, Subhadra; Herkenham, Miles.

Afiliación

Samuels JD; Section on Functional Neuroanatomy, Intramural Research Program, National Institute of Mental Health, National Institutes of Health, Bethesda, MD, 20892, USA. rhk9gh@virginia.edu.
Lotstein ML; Neuroscience Graduate Program, Department of Neuroscience, Center for Brain Immunology and Glia, University of Virginia, 409 Lane Road, MR-4 6154, Charlottesville, VA, 22908, USA. rhk9gh@virginia.edu.
Lehmann ML; Section on Functional Neuroanatomy, Intramural Research Program, National Institute of Mental Health, National Institutes of Health, Bethesda, MD, 20892, USA.
Elkahloun AG; Section on Functional Neuroanatomy, Intramural Research Program, National Institute of Mental Health, National Institutes of Health, Bethesda, MD, 20892, USA.
Banerjee S; Cancer Genetics and Comparative Genomics Branch, National Human Genome Research Institute, National Institutes of Health, Bethesda, MD, 20892, USA.
Herkenham M; Flow Cytometry Core, Laboratory of Genome Integrity, National Cancer Institute, National Institutes of Health, Bethesda, MD, 20892, USA.

J Neuroinflammation ; 20(1): 154, 2023 Jun 28.

Article en En | MEDLINE | ID: mdl-37380974

Asunto(s)

Encéfalo; Derrota Social; Animales; Ratones; Sistema Inmunológico; Barrera Hematoencefálica; Expresión Génica

Palabras clave

Cerebrovasculature; Immune activation; Psychosocial stress; Single-cell RNA sequencing; Vascular repair

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Encéfalo / Derrota Social Tipo de estudio: Risk_factors_studies Límite: Animals Idioma: En Revista: J Neuroinflammation Asunto de la revista: NEUROLOGIA Año: 2023 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Reino Unido

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