The effect of preoperative oral nutritional supplementation on surgical site infections among adult patients undergoing elective surgery: A systematic review and meta-analysis.
Am J Surg
; 226(3): 330-339, 2023 09.
Article
en En
| MEDLINE
| ID: mdl-37385857
ABSTRACT
INTRODUCTION:
Mixed findings are reported on the effect of oral nutritional supplements in reducing Surgical Site Infections (SSIs). MATERIAL ANDMETHODS:
PubMED, EMBASE and Cochrane were searched. Studies from inception to July 2022 were included if they involved adults undergoing elective surgery and compared preoperative macronutrient oral nutritional supplements to placebo/standard diet.RESULTS:
Of 372 unique citations, 19 were included (N â= â2480) 13 RCTs (N â= â1506) and 6 observational studies (N â= â974). Moderate-certainty evidence suggested that nutritional supplements SSI risk (OR 0.54, 95% C.I. 0.40-0.72, N â= â2718 participants). In elective colorectal surgery, this risk-reduction was 0.43 (95% C.I. 0.26-0.61, N â= â835 participants) and among patients who received Impact 0.48 (95% C.I. 0.32-0.70, N â= â1338).CONCLUSION:
Oral nutritional supplements prior to adult elective surgery may significantly reduce SSIs, with an overall 50% protective effect. This protective effect persisted in subgroup analysis of colorectal surgery patients and the use of Impact.Palabras clave
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Infección de la Herida Quirúrgica
/
Suplementos Dietéticos
Tipo de estudio:
Clinical_trials
/
Observational_studies
/
Systematic_reviews
Límite:
Adult
/
Humans
Idioma:
En
Revista:
Am J Surg
Año:
2023
Tipo del documento:
Article