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The effect of preoperative oral nutritional supplementation on surgical site infections among adult patients undergoing elective surgery: A systematic review and meta-analysis.
Cadili, Lina; van Dijk, Pim A D; Grudzinski, Alexa L; Cape, Jennifer; Kuhnen, Angela H.
Afiliación
  • Cadili L; Harvard T.H. Chan School of Public Health, Boston, MA, USA; Division of General Surgery, Department of General Surgery, University of British Columbia, Vancouver, British Columbia, Canada. Electronic address: lina.cadili@alumni.ubc.ca.
  • van Dijk PAD; Harvard T.H. Chan School of Public Health, Boston, MA, USA; Department of Orthopaedic Surgery, Academic Center for Evidence-based Sports Medicine (ACES) and Amsterdam Collaboration for Health and Safety in Sports, ACHSS, Amsterdam UMC IOC Research Center, University of Amsterdam, the Netherlands.
  • Grudzinski AL; Harvard T.H. Chan School of Public Health, Boston, MA, USA; Department of Anesthesiology and Pain Medicine, University of Ottawa, Ontario, Canada.
  • Cape J; Harvard T.H. Chan School of Public Health, Boston, MA, USA; Department of Plastic and Reconstructive Surgery, Western University, London, Ontario, Canada.
  • Kuhnen AH; Harvard T.H. Chan School of Public Health, Boston, MA, USA; Department of Colon and Rectal Surgery, Lahey Hospital, Tufts University School of Medicine, Burlington, MA, USA.
Am J Surg ; 226(3): 330-339, 2023 09.
Article en En | MEDLINE | ID: mdl-37385857
ABSTRACT

INTRODUCTION:

Mixed findings are reported on the effect of oral nutritional supplements in reducing Surgical Site Infections (SSIs). MATERIAL AND

METHODS:

PubMED, EMBASE and Cochrane were searched. Studies from inception to July 2022 were included if they involved adults undergoing elective surgery and compared preoperative macronutrient oral nutritional supplements to placebo/standard diet.

RESULTS:

Of 372 unique citations, 19 were included (N â€‹= â€‹2480) 13 RCTs (N â€‹= â€‹1506) and 6 observational studies (N â€‹= â€‹974). Moderate-certainty evidence suggested that nutritional supplements SSI risk (OR 0.54, 95% C.I. 0.40-0.72, N â€‹= â€‹2718 participants). In elective colorectal surgery, this risk-reduction was 0.43 (95% C.I. 0.26-0.61, N â€‹= â€‹835 participants) and among patients who received Impact 0.48 (95% C.I. 0.32-0.70, N â€‹= â€‹1338).

CONCLUSION:

Oral nutritional supplements prior to adult elective surgery may significantly reduce SSIs, with an overall 50% protective effect. This protective effect persisted in subgroup analysis of colorectal surgery patients and the use of Impact.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Infección de la Herida Quirúrgica / Suplementos Dietéticos Tipo de estudio: Clinical_trials / Observational_studies / Systematic_reviews Límite: Adult / Humans Idioma: En Revista: Am J Surg Año: 2023 Tipo del documento: Article
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Infección de la Herida Quirúrgica / Suplementos Dietéticos Tipo de estudio: Clinical_trials / Observational_studies / Systematic_reviews Límite: Adult / Humans Idioma: En Revista: Am J Surg Año: 2023 Tipo del documento: Article