Synthesis and properties of novel type I photosensitizer polycyclic amide.

Wang, Kui; Ye, Tao; Du, Haoyang; Jin, Xiangyu; Yi, Xiaofen; Gao, Huiying; Zhang, Yuan; Dong, Wei; Liu, Shihui; Guan, Jing; Lin, Feng; Xia, Debin

Wang, Kui; Ye, Tao; Du, Haoyang; Jin, Xiangyu; Yi, Xiaofen; Gao, Huiying; Zhang, Yuan; Dong, Wei; Liu, Shihui; Guan, Jing; Lin, Feng; Xia, Debin.

Afiliación

Wang K; Department of Organic Chemistry, College of Pharmacy, Harbin Medical University Harbin China guanjing@ems.hrbmu.edu.cn xiaolin_linfeng@126.com.
Ye T; Department of Organic Chemistry, College of Pharmacy, Harbin Medical University Harbin China guanjing@ems.hrbmu.edu.cn xiaolin_linfeng@126.com.
Du H; Department of Organic Chemistry, College of Pharmacy, Harbin Medical University Harbin China guanjing@ems.hrbmu.edu.cn xiaolin_linfeng@126.com.
Jin X; Department of Organic Chemistry, College of Pharmacy, Harbin Medical University Harbin China guanjing@ems.hrbmu.edu.cn xiaolin_linfeng@126.com.
Yi X; Department of Organic Chemistry, College of Pharmacy, Harbin Medical University Harbin China guanjing@ems.hrbmu.edu.cn xiaolin_linfeng@126.com.
Gao H; Department of Organic Chemistry, College of Pharmacy, Harbin Medical University Harbin China guanjing@ems.hrbmu.edu.cn xiaolin_linfeng@126.com.
Zhang Y; Department of Organic Chemistry, College of Pharmacy, Harbin Medical University Harbin China guanjing@ems.hrbmu.edu.cn xiaolin_linfeng@126.com.
Dong W; Department of Organic Chemistry, College of Pharmacy, Harbin Medical University Harbin China guanjing@ems.hrbmu.edu.cn xiaolin_linfeng@126.com.
Liu S; MIIT Key Laboratory of Critical Materials Technology for New Energy Conversion and Storage, School of Chemistry and Chemical Engineering, Harbin Institute of Technology Harbin China.
Guan J; Department of Organic Chemistry, College of Pharmacy, Harbin Medical University Harbin China guanjing@ems.hrbmu.edu.cn xiaolin_linfeng@126.com.
Lin F; Department of Organic Chemistry, College of Pharmacy, Harbin Medical University Harbin China guanjing@ems.hrbmu.edu.cn xiaolin_linfeng@126.com.
Xia D; MIIT Key Laboratory of Critical Materials Technology for New Energy Conversion and Storage, School of Chemistry and Chemical Engineering, Harbin Institute of Technology Harbin China.

Nanoscale Adv ; 5(14): 3629-3633, 2023 Jul 11.

Article en En | MEDLINE | ID: mdl-37441256

ABSTRACT

ABSTRACT

Herein, we have designed and synthesized a novel type-I photosensitizer (PhPA) via Rh-catalyzed oxidative cyclization of diacetoxyterephthalamide with alkynes. The photoelectric properties, photosensitivity and photodegradation process of PhPA have been systematically investigated. The remarkable fluorescence quenching effect (ΦPL < 0.01) of PhPA suggests that the intersystem crossing from the singlet excited state to the reactive triplet state is enhanced by the enlarged conjugated backbone. Additionally, the ability of superoxide radical (O2-Ë) generation was confirmed by electron paramagnetic resonance spectroscopy. Finally, the mechanism of PhPA photo-oxidative degradation via the structure of two metabolites is proposed.

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Nanoscale Adv Año: 2023 Tipo del documento: Article