Your browser doesn't support javascript.
loading
Intra- and Interspecies Differences of Two Cecropia Species from Tabasco, Mexico, Determined through the Metabolic Analysis and 1H-NMR-Based Fingerprinting of Hydroalcoholic Extracts.
Medrano-Sánchez, Eric Jaziel; Hernández-Bolio, Gloria Ivonne; Lobato-García, Carlos Ernesto; González-Cortazar, Manasés; Antunez-Mojica, Mayra; Gallegos-García, Ammy Joana; Barredo-Hernández, Cristian Octavio; López-Rodríguez, Ricardo; Aguilar-Sánchez, Nelly Cristina; Gómez-Rivera, Abraham.
Afiliación
  • Medrano-Sánchez EJ; División Académica de Ciencias Básicas, Universidad Juárez Autónoma de Tabasco, Carretera Cunduacán-Jalpa Km. 0.5, Cunduacán 86690, Tabasco, Mexico.
  • Hernández-Bolio GI; Departamento de Física Aplicada, Centro de Investigación y Estudios Avanzados del Instituto Politécnico Nacional, Unidad Mérida, Antigua Carretera a Progreso Km. 6, Mérida 97310, Yucatán, Mexico.
  • Lobato-García CE; División Académica de Ciencias Básicas, Universidad Juárez Autónoma de Tabasco, Carretera Cunduacán-Jalpa Km. 0.5, Cunduacán 86690, Tabasco, Mexico.
  • González-Cortazar M; Centro de Investigación Biomédica del Sur, Instituto Mexicano del Seguro Social, Argentina No. 1, Col. Centro, Xochitepec 62790, Morelos, Mexico.
  • Antunez-Mojica M; CONACYT-Centro de Investigaciones Químicas-IICBA, Universidad Autónoma del Estado de Morelos, Avenida Universidad 1001, Chamilpa, Cuernavaca 62209, Morelos, Mexico.
  • Gallegos-García AJ; División de Ciencias Básicas e Ingeniería, Universidad Popular de la Chontalpa-Carretera Cárdenas-Huimanguillo Km 2 S/N, Ranchería, Invitab Paso y Playa, Heroica, Cárdenas 86556, Tabasco, Mexico.
  • Barredo-Hernández CO; División Académica de Ciencias Básicas, Universidad Juárez Autónoma de Tabasco, Carretera Cunduacán-Jalpa Km. 0.5, Cunduacán 86690, Tabasco, Mexico.
  • López-Rodríguez R; División Académica de Ciencias Básicas, Universidad Juárez Autónoma de Tabasco, Carretera Cunduacán-Jalpa Km. 0.5, Cunduacán 86690, Tabasco, Mexico.
  • Aguilar-Sánchez NC; División Académica Multidisciplinaria de Jalpa de Méndez, Universidad Juárez Autónoma de Tabasco, Carretera Estatal Libre Villahermosa Comalcalco Km 27 S/N, Ranchería Rivera Alta, Jalpa de Méndez 86205, Tabasco, Mexico.
  • Gómez-Rivera A; División Académica de Ciencias Básicas, Universidad Juárez Autónoma de Tabasco, Carretera Cunduacán-Jalpa Km. 0.5, Cunduacán 86690, Tabasco, Mexico.
Plants (Basel) ; 12(13)2023 Jun 25.
Article en En | MEDLINE | ID: mdl-37447001
The genus Cecropia is used in the traditional medicine of Tabasco, Mexico, in diabetes and hypertension treatments, mainly without distinction of the species. This contribution aimed to carry out the metabolic analysis and Proton Nuclear Magnetic Resonance (1H-NMR) spectroscopy-based fingerprinting of the hydroalcoholic leaf extracts of Cecropia peltata (Cp) and Cecropia obtusifolia (Co) collected in five sub-regions of the State of Tabasco (Cp1, "Centro"; Cp2, "Chontalpa"; Cp3, "Pantanos"; Cp4, "Ríos" and Co5, "Sierra"). Firstly, the extracts were evaluated for their Total Phenol Content (TPC) and Total Flavonoid Content (TFC) by spectrophotometric methods. In addition, metabolic analysis was performed using High-Performance Liquid Chromatography with Diode-Array Detection HPLC-DAD, which allowed the quantification of the chemical markers: chlorogenic acid, isoorientin, and orientin, as well as a vitexin analog. Finally, metabolomic analysis was carried out based on the 1H-NMR spectra. The Cp4 extract (C. peltata from the "Ríos" sub-region) presented the highest values of TPC (155 ± 9.1 mg GAE/g E) and TFC (724 ± 22.2 mg RE/g E). The metabolic analysis was similar among the five samples; the highest concentrations of the four chemical markers were found in Cp3 (C. peltata from the "Pantanos" sub-region) for chlorogenic acid (39.8 ± 2.3 mg/g) and isoorientin (51.5 ± 2.9 mg/g), in Cp4 for orientin (49.9 ± 0.6 mg/g), and in Cp2 (C. peltata from the "Chontalpa" sub-region) for the vitexin analog (6.2 ± 0.2 mg/g). The metabolic analysis and the 1H-NMR fingerprint analysis showed intraspecies differences among the C. peltata samples and interspecies between C. peltata and C. obtusifolia, which were attributed to variations in the metabolite groups as well as in the proportion of sugars such as glucose and xylose.
Palabras clave

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE País/Región como asunto: Mexico Idioma: En Revista: Plants (Basel) Año: 2023 Tipo del documento: Article País de afiliación: México Pais de publicación: Suiza

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE País/Región como asunto: Mexico Idioma: En Revista: Plants (Basel) Año: 2023 Tipo del documento: Article País de afiliación: México Pais de publicación: Suiza