Number of segments with motion abnormalities is better correlated with infarct size in acute myocardial infarction.
Coron Artery Dis
; 34(7): 489-495, 2023 11 01.
Article
en En
| MEDLINE
| ID: mdl-37471279
ABSTRACT
BACKGROUND:
The relationship between the number of segments with motion abnormalities (SMA) on the bull's-eye plots of speckle-tracking echocardiography (STE) and myocardial infarct size (MIS) on late gadolinium-enhanced cardiac MRI (LGE-cMRI) has not been well characterized. This study aimed to determine MIS using the number of SMA in patients with acute myocardial infarction (MI).METHODS:
Left ventricular two-dimensional STE and LGE-cMRI were performed in 380 patients with ST-segment elevation MI within 48â h and 5-6â days after primary percutaneous intervention, respectively.RESULTS:
Patients with impaired global and regional myocardial strain, work and greater number of SMA had significantly larger infarcts ( P â <â 0.05). Multivariate logistic regression analysis that included myocardial strain, work, and number of SMA showed that total number of SMA [odds ratio (OR)â =â 1.976; 95% confidence interval (CI) 1.539-2.538, P â <â 0.0001], the number of segments with paradoxalic systolic movements (SPSM, ORâ =â 3.703; 95% CI 2.112-6.493, P â <â 0.0001) were independent risk factors of large MIS (>19%). The area under receiver operating characteristic curve (AUC) of 0.904 (0.866~0.942) for total number of SMA was superior to that for global longitudinal strain (GLS, AUCâ =â 0.813, 0.761~0.865), global work efficiency (GWE, AUCâ =â 0.794, 0.730~0.857) and number of SPSM (AUCâ =â 0.851, 0.804-0.899) to predict a large MIS ( P â <â 0.05). The optimal cutoff value of total number of SMA was 7, with a sensitivity of 85.31%, a specificity of 81.48%, and an accuracy of 83.27%.CONCLUSION:
Total number of SMA is better associated with infarct size, which provided an incremental prognostic value above established prognostic parameters such as GLS and GWE.
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Infarto del Miocardio con Elevación del ST
/
Infarto del Miocardio
Tipo de estudio:
Prognostic_studies
/
Risk_factors_studies
Límite:
Humans
Idioma:
En
Revista:
Coron Artery Dis
Asunto de la revista:
ANGIOLOGIA
/
CARDIOLOGIA
Año:
2023
Tipo del documento:
Article