Chemoselective Transformations of Amides: An Approach to Quinolones from ß-Amido Ynones.
Org Lett
; 25(31): 5762-5767, 2023 Aug 11.
Article
en En
| MEDLINE
| ID: mdl-37500499
ABSTRACT
An efficient and chemoselective transformation of ß-amido ynones to 3-acyl-substituted quinolones 2 and 3-H-quinolones 4 has been developed. In this reaction, ß-cyclic amido ynones can be selectively transformed into quinolones 2 in anhydrous EG via a selective CâO bond cleavage, 1,5-O migration, and CâC bond recombination process. The practical approach of this reaction renders it a viable alternative for the construction of various quinolones.
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Idioma:
En
Revista:
Org Lett
Asunto de la revista:
BIOQUIMICA
Año:
2023
Tipo del documento:
Article
País de afiliación:
China