Pregnancy prevalence and outcomes after optic neuritis in South Korea.
Sci Rep
; 13(1): 12167, 2023 07 27.
Article
en En
| MEDLINE
| ID: mdl-37500694
ABSTRACT
To compare pregnancy rates and complications in women with and without a history of optic neuritis (ON). A nationwide, population-based, retrospective study using data from the Korean National Health Claims from January 2011, to December 2017 was done. ON cohort (ON group) consisting of women aged 18 to 50 with a history of ON and 13 age-matched controls (control group) were compared for pregnancy and delivery rates using logistic regression after adjusting for possible confounders. Pregnancy-ON cohort (pregnancy-ON group), women aged 18 to 55 with a history of ON and pregnancy, and 13 age at pregnancy matched controls (pregnancy-control group) were analyzed for pregnancy complications using logistic regression after adjusting for covariates. ON group (n = 2516) showed decreased odds ratio (OR) for pregnancy [Adjusted OR2 0.716, 95% confidence interval (CI) 0.626-0.820] and delivery (adjusted OR2 0.647, 95% CI 0.554-0.756) compared to controls (n = 7548). Pregnancy-ON group (n = 550) showed increased risk of delayed fetal growth (adjusted OR2 9.867, 95% CI 1.224-79.564), pre-eclampsia (adjusted OR2 8.327, 95% CI 2.911-23.819), preterm delivery (adjusted OR2 3.914, 95% CI 2.667-5.742), pregnancy and postpartum infection (adjusted OR1 1.671, 95% CI 1.296-2.154), diabetes in pregnancy (adjusted OR2 1.365, 95% CI 1.062-1.754) compared to pregnancy-control group (n = 1650). Our population-based cohort study suggests that history of ON is associated with decreased pregnancy and delivery rates. It may be a risk factor for various pregnancy complications.
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Complicaciones del Embarazo
/
Neuritis Óptica
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Nacimiento Prematuro
Tipo de estudio:
Etiology_studies
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Incidence_studies
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Observational_studies
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Prevalence_studies
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Risk_factors_studies
Límite:
Female
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Humans
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Newborn
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Pregnancy
Idioma:
En
Revista:
Sci Rep
Año:
2023
Tipo del documento:
Article
Pais de publicación:
ENGLAND
/
ESCOCIA
/
GB
/
GREAT BRITAIN
/
INGLATERRA
/
REINO UNIDO
/
SCOTLAND
/
UK
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UNITED KINGDOM