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Precision Medicine Is Changing the Roles of Healthcare Professionals, Scientists, and Research Staff: Learnings from a Childhood Cancer Precision Medicine Trial.
Daly, Rebecca; Hetherington, Kate; Hazell, Emily; Wadling, Bethany R; Tyrrell, Vanessa; Tucker, Katherine M; Marshall, Glenn M; Ziegler, David S; Lau, Loretta M S; Trahair, Toby N; O'Brien, Tracey A; Collins, Kiri; Gifford, Andrew J; Haber, Michelle; Pinese, Mark; Malkin, David; Cowley, Mark J; Karpelowsky, Jonathan; Drew, Donna; Jacobs, Chris; Wakefield, Claire E.
Afiliación
  • Daly R; Discipline of Pediatrics and Child Health, School of Clinical Medicine, UNSW Medicine & Health, UNSW Sydney, Sydney, NSW 2052, Australia.
  • Hetherington K; Behavioural Sciences Unit, Kids Cancer Centre, Sydney Children's Hospital, Randwick, NSW 2031, Australia.
  • Hazell E; Discipline of Pediatrics and Child Health, School of Clinical Medicine, UNSW Medicine & Health, UNSW Sydney, Sydney, NSW 2052, Australia.
  • Wadling BR; Behavioural Sciences Unit, Kids Cancer Centre, Sydney Children's Hospital, Randwick, NSW 2031, Australia.
  • Tyrrell V; Discipline of Pediatrics and Child Health, School of Clinical Medicine, UNSW Medicine & Health, UNSW Sydney, Sydney, NSW 2052, Australia.
  • Tucker KM; Behavioural Sciences Unit, Kids Cancer Centre, Sydney Children's Hospital, Randwick, NSW 2031, Australia.
  • Marshall GM; Graduate School of Health, University of Technology Sydney, Sydney, NSW 2007, Australia.
  • Ziegler DS; Discipline of Pediatrics and Child Health, School of Clinical Medicine, UNSW Medicine & Health, UNSW Sydney, Sydney, NSW 2052, Australia.
  • Lau LMS; Behavioural Sciences Unit, Kids Cancer Centre, Sydney Children's Hospital, Randwick, NSW 2031, Australia.
  • Trahair TN; Graduate School of Health, University of Technology Sydney, Sydney, NSW 2007, Australia.
  • O'Brien TA; Discipline of Pediatrics and Child Health, School of Clinical Medicine, UNSW Medicine & Health, UNSW Sydney, Sydney, NSW 2052, Australia.
  • Collins K; Children's Cancer Institute, UNSW Sydney, Sydney, NSW 2052, Australia.
  • Gifford AJ; Hereditary Cancer Centre, Department of Medical Oncology, Prince of Wales Hospital, Randwick, NSW 2031, Australia.
  • Haber M; Prince of Wales Clinical School, UNSW Sydney, Randwick, NSW 2031, Australia.
  • Pinese M; Discipline of Pediatrics and Child Health, School of Clinical Medicine, UNSW Medicine & Health, UNSW Sydney, Sydney, NSW 2052, Australia.
  • Malkin D; Children's Cancer Institute, UNSW Sydney, Sydney, NSW 2052, Australia.
  • Cowley MJ; Kids Cancer Centre, Sydney Children's Hospital, Randwick, NSW 2031, Australia.
  • Karpelowsky J; Discipline of Pediatrics and Child Health, School of Clinical Medicine, UNSW Medicine & Health, UNSW Sydney, Sydney, NSW 2052, Australia.
  • Drew D; Children's Cancer Institute, UNSW Sydney, Sydney, NSW 2052, Australia.
  • Jacobs C; Kids Cancer Centre, Sydney Children's Hospital, Randwick, NSW 2031, Australia.
  • Wakefield CE; Discipline of Pediatrics and Child Health, School of Clinical Medicine, UNSW Medicine & Health, UNSW Sydney, Sydney, NSW 2052, Australia.
J Pers Med ; 13(7)2023 Jun 23.
Article en En | MEDLINE | ID: mdl-37511646
ABSTRACT
Precision medicine programs aim to utilize novel technologies to identify personalized treatments for children with cancer. Delivering these programs requires interdisciplinary efforts, yet the many groups involved are understudied. This study explored the experiences of a broad range of professionals delivering Australia's first precision medicine trial for children with poor-prognosis cancer the PRecISion Medicine for Children with Cancer (PRISM) national clinical trial of the Zero Childhood Cancer Program. We conducted semi-structured interviews with 85 PRISM professionals from eight professional groups, including oncologists, surgeons, clinical research associates, scientists, genetic professionals, pathologists, animal care technicians, and nurses. We analyzed interviews thematically. Professionals shared that precision medicine can add complexity to their role and result in less certain outcomes for families. Although many participants described experiencing a greater emotional impact from their work, most expressed very positive views about the impact of precision medicine on their profession and its future potential. Most reported navigating precision medicine without formal training. Each group described unique challenges involved in adapting to precision medicine in their profession. Addressing training gaps and meeting the specific needs of many professional groups involved in precision medicine will be essential to ensure the successful implementation of standard care.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Tipo de estudio: Qualitative_research Idioma: En Revista: J Pers Med Año: 2023 Tipo del documento: Article País de afiliación: Australia
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Tipo de estudio: Qualitative_research Idioma: En Revista: J Pers Med Año: 2023 Tipo del documento: Article País de afiliación: Australia