Controlling antifungal activity with light: Optical regulation of fungal ergosterol biosynthetic pathway with photo-responsive CYP51 inhibitors.

Li, Zhuang; Liu, Na; Yang, Wanzhen; Tu, Jie; Huang, Yahui; Wang, Wei; Sheng, Chunquan

Li, Zhuang; Liu, Na; Yang, Wanzhen; Tu, Jie; Huang, Yahui; Wang, Wei; Sheng, Chunquan.

Afiliación

Li Z; State Key Laboratory of Bioengineering Reactor, And Shanghai Key Laboratory of New Drug Design, School of Pharmacy, East China University of Science & Technology, Shanghai 200237, China.
Liu N; School of Pharmacy, Second Military Medical University (Naval Medical University), Shanghai 200433, China.
Yang W; School of Pharmacy, Second Military Medical University (Naval Medical University), Shanghai 200433, China.
Tu J; School of Pharmacy, Second Military Medical University (Naval Medical University), Shanghai 200433, China.
Huang Y; School of Pharmacy, Second Military Medical University (Naval Medical University), Shanghai 200433, China.
Wang W; State Key Laboratory of Bioengineering Reactor, And Shanghai Key Laboratory of New Drug Design, School of Pharmacy, East China University of Science & Technology, Shanghai 200237, China.
Sheng C; Department of Pharmacology and Toxicology, College of Pharmacy, And BIO5 Institute, University of Arizona, Tucson, AZ 85721, USA.

Acta Pharm Sin B ; 13(7): 3080-3092, 2023 Jul.

Article en En | MEDLINE | ID: mdl-37521860

Palabras clave

Antifungal agents; Ergosterol biosynthesis; Optical control; Photocaged; Triazoles

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Acta Pharm Sin B Año: 2023 Tipo del documento: Article País de afiliación: China Pais de publicación: Países Bajos

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