Descending dopaminergic pathway facilitates itch signal processing via activating spinal GRPR<sup>+</sup> neurons.

Zhang, Zhi-Jun; Shao, Han-Yu; Liu, Chuan; Song, Hao-Lin; Wu, Xiao-Bo; Cao, De-Li; Zhu, Meixuan; Fu, Yuan-Yuan; Wang, Juan; Gao, Yong-Jing

Descending dopaminergic pathway facilitates itch signal processing via activating spinal GRPR⁺ neurons.

Zhang, Zhi-Jun; Shao, Han-Yu; Liu, Chuan; Song, Hao-Lin; Wu, Xiao-Bo; Cao, De-Li; Zhu, Meixuan; Fu, Yuan-Yuan; Wang, Juan; Gao, Yong-Jing.

Afiliación

Zhang ZJ; Institute of Pain Medicine and Special Environmental Medicine, Co-Innovation Center of Neuroregeneration, Nantong University, Jiangsu, China.
Shao HY; Department of Human Anatomy, School of Medicine, Nantong University, Jiangsu, China.
Liu C; Department of Human Anatomy, School of Medicine, Nantong University, Jiangsu, China.
Song HL; Department of Human Anatomy, School of Medicine, Nantong University, Jiangsu, China.
Wu XB; Department of Human Anatomy, School of Medicine, Nantong University, Jiangsu, China.
Cao DL; Institute of Pain Medicine and Special Environmental Medicine, Co-Innovation Center of Neuroregeneration, Nantong University, Jiangsu, China.
Zhu M; Institute of Pain Medicine and Special Environmental Medicine, Co-Innovation Center of Neuroregeneration, Nantong University, Jiangsu, China.
Fu YY; University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
Wang J; Institute of Pain Medicine and Special Environmental Medicine, Co-Innovation Center of Neuroregeneration, Nantong University, Jiangsu, China.
Gao YJ; Department of Human Anatomy, School of Medicine, Nantong University, Jiangsu, China.

EMBO Rep ; 24(10): e56098, 2023 10 09.

Article en En | MEDLINE | ID: mdl-37522391

Asunto(s)

Receptores de Bombesina; Médula Espinal; Humanos; Receptores de Bombesina/genética; Receptores de Bombesina/metabolismo; Péptido Liberador de Gastrina/genética; Péptido Liberador de Gastrina/metabolismo; Médula Espinal/metabolismo; Ácido Glutámico/metabolismo; Dopamina/metabolismo; Prurito/genética; Prurito/metabolismo; Neuronas Dopaminérgicas/metabolismo; Receptores AMPA/genética; Receptores AMPA/metabolismo

Palabras clave

A11; DRD1; GRP; dopamine; itch

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Médula Espinal / Receptores de Bombesina Límite: Humans Idioma: En Revista: EMBO Rep Asunto de la revista: BIOLOGIA MOLECULAR Año: 2023 Tipo del documento: Article País de afiliación: China Pais de publicación: Reino Unido

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