Self-micellizing solid dispersion of tacrolimus: Physicochemical and pharmacokinetic characterization.

Makino, Keisuke; Tsukada, Ryota; Kambayashi, Atsushi; Yamada, Kohei; Sato, Hideyuki; Onoue, Satomi

Makino, Keisuke; Tsukada, Ryota; Kambayashi, Atsushi; Yamada, Kohei; Sato, Hideyuki; Onoue, Satomi.

Afiliación

Makino K; Laboratory of Biopharmacy, School of Pharmaceutical Sciences, University of Shizuoka, Shizuoka, Japan.
Tsukada R; Laboratory of Biopharmacy, School of Pharmaceutical Sciences, University of Shizuoka, Shizuoka, Japan.
Kambayashi A; Laboratory of Biopharmacy, School of Pharmaceutical Sciences, University of Shizuoka, Shizuoka, Japan.
Yamada K; Pharmaceutical Research and Technology Labs, Astellas Pharma Inc., Shizuoka, Japan.
Sato H; Department of Medicinal and Life Science, Faculty of Pharmaceutical Sciences, Tokyo University of Science, Chiba, Japan.
Onoue S; Laboratory of Biopharmacy, School of Pharmaceutical Sciences, University of Shizuoka, Shizuoka, Japan.

Biopharm Drug Dispos ; 44(6): 387-395, 2023 Dec.

Article en En | MEDLINE | ID: mdl-37526477

Asunto(s)

Polietilenglicoles; Tacrolimus; Ratas; Animales; Ratas Sprague-Dawley; Solubilidad; Micelas; Disponibilidad Biológica; Administración Oral

Palabras clave

oral bioavailability; self-micellizing solid dispersion; stability; tacrolimus

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Polietilenglicoles / Tacrolimus Límite: Animals Idioma: En Revista: Biopharm Drug Dispos Año: 2023 Tipo del documento: Article País de afiliación: Japón Pais de publicación: Reino Unido

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