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A water-soluble fluorescent organic nano-photosensitizer for the ratiometric detection of mitochondrial G-quadruplexes with photodynamic therapy potential.
Ma, Qing-Yu; Li, Xiang; Zhou, Wei; Li, Xia-Fen; Liu, Yi-Chen; Feng, Gai-Li; Tan, Hongwei; Zhang, Yuan; Xing, Guo-Wen.
Afiliación
  • Ma QY; College of Chemistry, Beijing Normal University, Beijing, 100875, China. yuanzhang@bnu.edu.cn.
  • Li X; College of Chemistry, Beijing Normal University, Beijing, 100875, China. yuanzhang@bnu.edu.cn.
  • Zhou W; College of Chemistry, Beijing Normal University, Beijing, 100875, China. yuanzhang@bnu.edu.cn.
  • Li XF; College of Chemistry, Beijing Normal University, Beijing, 100875, China. yuanzhang@bnu.edu.cn.
  • Liu YC; College of Chemistry, Beijing Normal University, Beijing, 100875, China. yuanzhang@bnu.edu.cn.
  • Feng GL; College of Chemistry, Beijing Normal University, Beijing, 100875, China. yuanzhang@bnu.edu.cn.
  • Tan H; College of Chemistry, Beijing Normal University, Beijing, 100875, China. yuanzhang@bnu.edu.cn.
  • Zhang Y; College of Chemistry, Beijing Normal University, Beijing, 100875, China. yuanzhang@bnu.edu.cn.
  • Xing GW; Key Laboratory of Energy Conversion and Storage Materials, College of Chemistry, Beijing Normal University, Beijing, 100875, China.
Chem Commun (Camb) ; 59(68): 10287-10290, 2023 Aug 22.
Article en En | MEDLINE | ID: mdl-37539814
ABSTRACT
We report a water-soluble AIEgen (TPAL) that can self-assemble into fluorescent organic nanoparticles for the ratiometric detection of mitochondrial DNA (mtDNA) parallel G-quadruplexes (G4s) with high selectivity, a low detection limit and photodynamic therapy (PDT) potential.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Fotoquimioterapia / G-Cuádruplex Tipo de estudio: Diagnostic_studies Idioma: En Revista: Chem Commun (Camb) Asunto de la revista: QUIMICA Año: 2023 Tipo del documento: Article País de afiliación: China
Texto completo
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XML
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Fotoquimioterapia / G-Cuádruplex Tipo de estudio: Diagnostic_studies Idioma: En Revista: Chem Commun (Camb) Asunto de la revista: QUIMICA Año: 2023 Tipo del documento: Article País de afiliación: China