Self-reported sleep in relation to risk of dementia a quarter of a century later at age 90+: The 90+ Study.
Behav Sleep Med
; 21(5): 620-632, 2023 09 03.
Article
en En
| MEDLINE
| ID: mdl-37540023
ABSTRACT
OBJECTIVE:
To examine sex-specific associations of sleep duration and napping self-reported at mean age of 69 years (range 53-81) with risk of incident dementia 24 years later at age 90 +.METHOD:
Analytic sample included individuals from a population-based study who reported sleep and napping once in the 1980s and 24 years later (range 16-38) joined The 90+ Study and were evaluated in-person. Those without dementia at baseline of The 90+ Study were prospectively followed. Hazard ratios [HR] and 95% confidence intervals [CI] of dementia risk were estimated by Cox regression.RESULTS:
Of 574 participants 71% were women, mean age at start of dementia follow-up with The 90+ Study was 93 years (range 90-102). After 3.3 years (range 0.4-13.8) of follow-up 47% developed dementia. Higher risk of dementia at age 90+ was seen in women with <6 hours of self-reported sleep per night (adjusted HR = 2.00; 95% CI = 1.15-3.50; p = .01) compared with 8 hours. Lower risk of dementia at 90+ was seen in men with short-to-moderate (<60 minutes) self-reported naps compared with no naps (HR = 0.33; 95% CI = 0.18-0.63; p < .01).CONCLUSIONS:
Sleep and nap 24 years earlier are important risk factors for dementia after age 90.
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Sueño
/
Demencia
Tipo de estudio:
Etiology_studies
/
Risk_factors_studies
Límite:
Aged
/
Aged80
/
Female
/
Humans
/
Male
Idioma:
En
Revista:
Behav Sleep Med
Asunto de la revista:
CIENCIAS DO COMPORTAMENTO
/
NEUROLOGIA
/
PSICOFISIOLOGIA
Año:
2023
Tipo del documento:
Article
País de afiliación:
Estados Unidos