Characterization and active component identification of Premna herbacea roxb. root extract reveals anti-inflammatory effect and amelioration of imiquimod induced psoriasis via modulation of macrophage inflammatory response.

Sarkar, Debanjan; Gorai, Partha; Pramanik, Anik; Mondal, Arghadip; Mondal, Naba Kumar; Modak, Biplob Kr; Bhattacharyya, Sankar

Sarkar, Debanjan; Gorai, Partha; Pramanik, Anik; Mondal, Arghadip; Mondal, Naba Kumar; Modak, Biplob Kr; Bhattacharyya, Sankar.

Afiliación

Sarkar D; Department of Zoology, Immunobiology and Translational Medicine Laboratory, Sidho Kanho Birsha University, Purulia 723104, India.
Gorai P; Department of Zoology, Parasitology Laboratory, Sidho Kanho Birsha University, Purulia 723104, India.
Pramanik A; Department of Zoology, Immunobiology and Translational Medicine Laboratory, Sidho Kanho Birsha University, Purulia 723104, India.
Mondal A; Department of Environmental Science, Environmental Chemistry Laboratory, The University of Burdwan, West Bengal 713104, India.
Mondal NK; Department of Environmental Science, Environmental Chemistry Laboratory, The University of Burdwan, West Bengal 713104, India.
Modak BK; Department of Zoology, Parasitology Laboratory, Sidho Kanho Birsha University, Purulia 723104, India. Electronic address: bkmodak20@skbu.ac.in.
Bhattacharyya S; Department of Zoology, Immunobiology and Translational Medicine Laboratory, Sidho Kanho Birsha University, Purulia 723104, India. Electronic address: sankar-bhattacharyya@skbu.ac.in.

Phytomedicine ; 119: 155007, 2023 Oct.

Article en En | MEDLINE | ID: mdl-37549537

Asunto(s)

Psoriasis; Ratones; Humanos; Animales; Imiquimod; Simulación del Acoplamiento Molecular; Ratones Endogámicos BALB C; Psoriasis/inducido químicamente; Psoriasis/tratamiento farmacológico; Piel; Inflamación/inducido químicamente; Inflamación/tratamiento farmacológico; Antiinflamatorios/farmacología; Antiinflamatorios/uso terapéutico; Extractos Vegetales/farmacología; Extractos Vegetales/uso terapéutico; Macrófagos/metabolismo; Modelos Animales de Enfermedad; Citocinas/metabolismo

Palabras clave

Chronic inflammation; Imiquimod induced psoriasis; Macrophages; NFκB; Premna herbacea root methanolic extract (PHRME); Prostaglandin

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Psoriasis Tipo de estudio: Diagnostic_studies / Prognostic_studies Límite: Animals / Humans Idioma: En Revista: Phytomedicine Asunto de la revista: TERAPIAS COMPLEMENTARES Año: 2023 Tipo del documento: Article País de afiliación: India Pais de publicación: Alemania

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