FeCl3-catalyzed oxidative amidation of benzylic C-H bonds enabled by a photogenerated chlorine-radical.
Chem Commun (Camb)
; 59(68): 10299-10302, 2023 Aug 22.
Article
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| MEDLINE
| ID: mdl-37551442
ABSTRACT
Herein, we report the development of iron-catalyzed benzylic C-H oxidative amidation reactions via photoinduced ligand-to-metal charge transfer (LMCT). These reactions exhibit a broad substrate scope (60 examples) and offer operationally simple, scalable procedures for accessing valuable products from methylarenes in a single step. Mechanistic studies and control experiments confirm the participation of a photogenerated chlorine radical in facilitating the hydrogen atom transfer (HAT) from the benzylic C-H bond to initiate the reaction.
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Colección:
01-internacional
Base de datos:
MEDLINE
Idioma:
En
Revista:
Chem Commun (Camb)
Asunto de la revista:
QUIMICA
Año:
2023
Tipo del documento:
Article