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Cryo-EM structures of Uba7 reveal the molecular basis for ISG15 activation and E1-E2 thioester transfer.
Afsar, Mohammad; Liu, GuanQun; Jia, Lijia; Ruben, Eliza A; Nayak, Digant; Sayyad, Zuberwasim; Bury, Priscila Dos Santos; Cano, Kristin E; Nayak, Anindita; Zhao, Xiang Ru; Shukla, Ankita; Sung, Patrick; Wasmuth, Elizabeth V; Gack, Michaela U; Olsen, Shaun K.
Afiliación
  • Afsar M; Department of Biochemistry & Structural Biology, University of Texas Health Science Center at San Antonio, San Antonio, TX, 78229, USA.
  • Liu G; Florida Research and Innovation Center, Cleveland Clinic, Port Saint Lucie, FL, 34987, USA.
  • Jia L; Department of Biochemistry & Structural Biology, University of Texas Health Science Center at San Antonio, San Antonio, TX, 78229, USA.
  • Ruben EA; Department of Biochemistry & Structural Biology, University of Texas Health Science Center at San Antonio, San Antonio, TX, 78229, USA.
  • Nayak D; Department of Biochemistry & Structural Biology, University of Texas Health Science Center at San Antonio, San Antonio, TX, 78229, USA.
  • Sayyad Z; Florida Research and Innovation Center, Cleveland Clinic, Port Saint Lucie, FL, 34987, USA.
  • Bury PDS; Department of Biochemistry & Structural Biology, University of Texas Health Science Center at San Antonio, San Antonio, TX, 78229, USA.
  • Cano KE; Department of Biochemistry & Structural Biology, University of Texas Health Science Center at San Antonio, San Antonio, TX, 78229, USA.
  • Nayak A; Department of Biochemistry & Structural Biology, University of Texas Health Science Center at San Antonio, San Antonio, TX, 78229, USA.
  • Zhao XR; Department of Biochemistry & Structural Biology, University of Texas Health Science Center at San Antonio, San Antonio, TX, 78229, USA.
  • Shukla A; Department of Biochemistry & Structural Biology, University of Texas Health Science Center at San Antonio, San Antonio, TX, 78229, USA.
  • Sung P; Department of Biochemistry & Structural Biology, University of Texas Health Science Center at San Antonio, San Antonio, TX, 78229, USA.
  • Wasmuth EV; Department of Biochemistry & Structural Biology, University of Texas Health Science Center at San Antonio, San Antonio, TX, 78229, USA.
  • Gack MU; Florida Research and Innovation Center, Cleveland Clinic, Port Saint Lucie, FL, 34987, USA.
  • Olsen SK; Department of Biochemistry & Structural Biology, University of Texas Health Science Center at San Antonio, San Antonio, TX, 78229, USA. olsens@uthscsa.edu.
Nat Commun ; 14(1): 4786, 2023 08 08.
Article en En | MEDLINE | ID: mdl-37553340

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Citocinas / Enzimas Ubiquitina-Conjugadoras Límite: Humans Idioma: En Revista: Nat Commun Asunto de la revista: BIOLOGIA / CIENCIA Año: 2023 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Reino Unido

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Citocinas / Enzimas Ubiquitina-Conjugadoras Límite: Humans Idioma: En Revista: Nat Commun Asunto de la revista: BIOLOGIA / CIENCIA Año: 2023 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Reino Unido