Identification and characterization of topoisomerase III beta poisons.

Wang, Wenjie; Saha, Sourav; Yang, Xi; Pommier, Yves; Huang, Shar-Yin N

Wang, Wenjie; Saha, Sourav; Yang, Xi; Pommier, Yves; Huang, Shar-Yin N.

Afiliación

Wang W; Laboratory of Molecular Pharmacology, Developmental Therapeutics Branch, Center for Cancer Research, National Cancer Institute, NIH, Bethesda, MD 20892.
Saha S; Laboratory of Molecular Pharmacology, Developmental Therapeutics Branch, Center for Cancer Research, National Cancer Institute, NIH, Bethesda, MD 20892.
Yang X; Laboratory of Molecular Pharmacology, Developmental Therapeutics Branch, Center for Cancer Research, National Cancer Institute, NIH, Bethesda, MD 20892.
Pommier Y; Laboratory of Molecular Pharmacology, Developmental Therapeutics Branch, Center for Cancer Research, National Cancer Institute, NIH, Bethesda, MD 20892.
Huang SN; Laboratory of Molecular Pharmacology, Developmental Therapeutics Branch, Center for Cancer Research, National Cancer Institute, NIH, Bethesda, MD 20892.

Proc Natl Acad Sci U S A ; 120(34): e2218483120, 2023 08 22.

Article en En | MEDLINE | ID: mdl-37579177

Asunto(s)

ADN-Topoisomerasas de Tipo I; Inhibidores de Topoisomerasa I; Línea Celular; ADN-Topoisomerasas de Tipo I/metabolismo; ARN; Inhibidores de Topoisomerasa I/química

Palabras clave

TOP3B; anti-cancer; inhibitor screen

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: ADN-Topoisomerasas de Tipo I / Inhibidores de Topoisomerasa I Tipo de estudio: Diagnostic_studies Idioma: En Revista: Proc Natl Acad Sci U S A Año: 2023 Tipo del documento: Article Pais de publicación: Estados Unidos

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