Topical carbonic anhydrase inhibitors closing bilateral secondary macular holes and a review of literature.
Retin Cases Brief Rep
; 2023 Aug 08.
Article
en En
| MEDLINE
| ID: mdl-37582334
ABSTRACT
PURPOSE:
To present a rare occurrence of bilateral macular hole secondary to vitrectomy that was successfully treated with topical carbonic anhydrase inhibitors and to review the literature for this phenomenon.METHODS:
Monthly clinical examination and optical coherence tomography (OCT) was conducted before and after eight weeks of topical 2% dorzolamide administered twice a day.RESULTS:
A 62-year-old male that had bilateral giant retinal tears which were repaired with vitrectomy subsequently presented with bilateral small macular holes of size 74 and 78 microns. Patient was trialled on 2% topical dorzolamide twice a day and reviewed monthly with OCT scans. Macular hole closure was identified after four weeks of topical treatment.Conclusion:
Clinical improvement with conservative measures suggests a potential first line approach to the treatment of macular holes avoiding surgery and its risk profile. We also present a review of literature regarding macular holes treated with topical carbonic anhydrase inhibitors and its mechanism of action in treating macular holes.
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Idioma:
En
Revista:
Retin Cases Brief Rep
Año:
2023
Tipo del documento:
Article
País de afiliación:
Australia