Successful experience of tofacitinib treatment in patients with Fibrodysplasia Ossificans Progressiva.
Pediatr Rheumatol Online J
; 21(1): 92, 2023 Aug 29.
Article
en En
| MEDLINE
| ID: mdl-37644581
ABSTRACT
Fibrodysplasia ossificans progressive (FOP) is an ultra-rare genetic disorder that is caused by a mutation in the ACVR1 gene and provokes severe heterotopic ossification. Since flares of the disease are associated with inflammation, it is assumed that JAK inhibitors can control active FOP due to blocking multiple signaling pathways.
Palabras clave
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Miositis Osificante
Límite:
Humans
Idioma:
En
Revista:
Pediatr Rheumatol Online J
Año:
2023
Tipo del documento:
Article
País de afiliación:
Rusia