Progressive Multifocal Encephalopathy Holmes Tremor Successfully Treated with Bilateral Deep Brain Stimulation.
Tremor Other Hyperkinet Mov (N Y)
; 13: 31, 2023.
Article
en En
| MEDLINE
| ID: mdl-37663532
ABSTRACT
Background:
We report a patient with bilateral HT treated with DBS. Case report A 58-year-old man diagnosed with HIV/AIDS and progressive multifocal leukoencephalopathy (PML) presented with 20 years of bilateral arm tremor refractory to therapy. DBS was implanted on the left ventral intermediate nucleus and posterior subthalamic area (VIM/PSA). One year later, a right VIM/PSA DBS was implanted. At twelve months, there were no significant side-effects. With his DBS turned off and on, the Fahn-Tolosa-Marin scale was rated 82 and 58, respectively.Discussion:
To our knowledge, this is the first report of bilateral DBS VIM/PSA treating HT with no significant side effects. Highlights We report a successful treatment using deep brain stimulation of bilateral Holmes tremor that was caused by progressive multifocal encephalopathy. The patient achieved 30% improvement in tremor control with a meaningful improvement in his activities of daily living.Palabras clave
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Encefalopatías
/
Estimulación Encefálica Profunda
Límite:
Humans
/
Male
/
Middle aged
Idioma:
En
Revista:
Tremor Other Hyperkinet Mov (N Y)
Año:
2023
Tipo del documento:
Article
País de afiliación:
Estados Unidos