4E-BP1 expression in embryonic postmitotic neurons mitigates mTORC1-induced cortical malformations and behavioral seizure severity but does not prevent epilepsy in mice.

Nguyen, Lena H; Sharma, Manas; Bordey, Angelique

Nguyen, Lena H; Sharma, Manas; Bordey, Angelique.

Afiliación

Nguyen LH; Department of Neuroscience, School of Behavioral and Brain Sciences, University of Texas at Dallas, Richardson, TX, United States.
Sharma M; Departments of Neurosurgery and Cellular & Molecular Physiology, Wu Tsai Institute, Yale University School of Medicine, New Haven, CT, United States.
Bordey A; Departments of Neurosurgery and Cellular & Molecular Physiology, Wu Tsai Institute, Yale University School of Medicine, New Haven, CT, United States.

Front Neurosci ; 17: 1257056, 2023.

Article en En | MEDLINE | ID: mdl-37680968

Palabras clave

4E-BP; cortical development; corticogenesis; epilepsy; mTOR; malformation of cortical development; seizures

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Front Neurosci Año: 2023 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Suiza

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