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Potential antibacterial and antioxidant inhibitory activities of Silybum marianum mediated biosynthesised He-Ne laser.
Aldayel, Munirah F.
Afiliación
  • Aldayel MF; Department of Biological Sciences, College of Science, King Faisal University, Al-Ahsa 31982, Saudi Arabia.
Saudi J Biol Sci ; 30(11): 103795, 2023 Nov.
Article en En | MEDLINE | ID: mdl-37692328
ABSTRACT
A potentially beneficial method in laser irradiation is currently gaining popularity. The biosynthesis of low-power lasers has also been applied to the therapy of disease in biological tissues. This study used laser pre-treatments of Silybum marianum (S. marianum) fruit extract as a stabilising agent to bio-fabricate a low-power laser. The silybin A and silybin B of the S. marianum fruit, which are derived from seedlings before S. marianum undergoes therapy with an He-Ne laser at various intervals, were assessed for their expressive properties in this study. The findings revealed that 6-min laser pre-treatments increased silybin A + B and bacterial inhibition and improved the medicinal property of S. marianum. The analysis of the reaction records was performed using ultraviolet-visible spectroscopy. The minimum inhibitory concentration (MIC) limit for the sphere dispersion approach's antimicrobial effect on the microorganisms under investigation was 50 to 100 g/mL. With an IC50 of 0.69 mg/mL, the laser-treated S. marianum (6 min) demonstrated radical scavenging activity. At MIC concentration, the laser-treated S. marianum (6 min) did not exhibit cytotoxicity in the MCF-7 cell line. Additionally, Salmonella typhi, methicillin-resistant Staphylococcus aureus (MRSA), and E. coli were more susceptible to the antimicrobial effects of ethanolic fruit extract with a greater silybin level. It was observed that the laser-treated S. marianum (6 min) showed beneficial antioxidant and antibacterial properties and could be employed without risk in several medical applications.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Saudi J Biol Sci Año: 2023 Tipo del documento: Article País de afiliación: Arabia Saudita

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Saudi J Biol Sci Año: 2023 Tipo del documento: Article País de afiliación: Arabia Saudita
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