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Abnormal blood microbiota profiles are associated with inflammation and immune restoration in HIV/AIDS individuals.
Guo, Xiaoyan; Wang, Zerui; Qu, Mengmeng; Guo, Yuntian; Yu, Minrui; Hong, Weiguo; Zhang, Chao; Fan, Xing; Song, Jinwen; Xu, Ruonan; Zhang, Jiyuan; Huang, Huihuang; Linghu, Enqiang; Wang, Fu-Sheng; Sun, Lijun; Jiao, Yan-Mei.
Afiliación
  • Guo X; Senior Department of Infectious Diseases, The Fifth Medical Center of Chinese PLA General Hospital, National Clinical Research Center for Infectious Diseases , Beijing, China.
  • Wang Z; Department of Gastroenterology, First Medical Center of Chinese PLA General Hospital , Beijing, China.
  • Qu M; Senior Department of Infectious Diseases, The Fifth Medical Center of Chinese PLA General Hospital, National Clinical Research Center for Infectious Diseases , Beijing, China.
  • Guo Y; Senior Department of Infectious Diseases, The Fifth Medical Center of Chinese PLA General Hospital, National Clinical Research Center for Infectious Diseases , Beijing, China.
  • Yu M; Senior Department of Infectious Diseases, The Fifth Medical Center of Chinese PLA General Hospital, National Clinical Research Center for Infectious Diseases , Beijing, China.
  • Hong W; Senior Department of Infectious Diseases, The Fifth Medical Center of Chinese PLA General Hospital, National Clinical Research Center for Infectious Diseases , Beijing, China.
  • Zhang C; Senior Department of Infectious Diseases, The Fifth Medical Center of Chinese PLA General Hospital, National Clinical Research Center for Infectious Diseases , Beijing, China.
  • Fan X; Senior Department of Infectious Diseases, The Fifth Medical Center of Chinese PLA General Hospital, National Clinical Research Center for Infectious Diseases , Beijing, China.
  • Song J; Senior Department of Infectious Diseases, The Fifth Medical Center of Chinese PLA General Hospital, National Clinical Research Center for Infectious Diseases , Beijing, China.
  • Xu R; Senior Department of Infectious Diseases, The Fifth Medical Center of Chinese PLA General Hospital, National Clinical Research Center for Infectious Diseases , Beijing, China.
  • Zhang J; Senior Department of Infectious Diseases, The Fifth Medical Center of Chinese PLA General Hospital, National Clinical Research Center for Infectious Diseases , Beijing, China.
  • Huang H; Senior Department of Infectious Diseases, The Fifth Medical Center of Chinese PLA General Hospital, National Clinical Research Center for Infectious Diseases , Beijing, China.
  • Linghu E; Department of Gastroenterology, First Medical Center of Chinese PLA General Hospital , Beijing, China.
  • Wang F-S; Senior Department of Infectious Diseases, The Fifth Medical Center of Chinese PLA General Hospital, National Clinical Research Center for Infectious Diseases , Beijing, China.
  • Sun L; Center for Infectious Diseases, Beijing Youan Hospital, Capital Medical University , Beijing, China.
  • Jiao Y-M; Senior Department of Infectious Diseases, The Fifth Medical Center of Chinese PLA General Hospital, National Clinical Research Center for Infectious Diseases , Beijing, China.
mSystems ; 8(5): e0046723, 2023 Oct 26.
Article en En | MEDLINE | ID: mdl-37698407
ABSTRACT
IMPORTANCE The characteristics of blood microbiota in HIV-infected individuals and their relevance to disease progression are still unknown, despite alterations in gut microbiota diversity and composition in HIV-infected individuals. Here, we present evidence of increased blood microbiota diversity in HIV-infected individuals, which may result from gut microbiota translocation. Also, we identify a group of microbes, Porphyromonas gingivalis, Prevotella sp. CAG5226, Eubacterium sp. CAG251, Phascolarctobacterium succinatutens, Anaerobutyricum hallii, Prevotella sp. AM34-19LB, and Phocaeicola plebeius, which are linked to poor immunological recovery. This work provides a scientific foundation toward therapeutic strategies targeting blood microbiota for immune recovery of HIV infection.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Infecciones por VIH / Síndrome de Inmunodeficiencia Adquirida / Microbiota / Reconstitución Inmune Tipo de estudio: Prognostic_studies / Risk_factors_studies Límite: Humans Idioma: En Revista: MSystems Año: 2023 Tipo del documento: Article País de afiliación: China
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Infecciones por VIH / Síndrome de Inmunodeficiencia Adquirida / Microbiota / Reconstitución Inmune Tipo de estudio: Prognostic_studies / Risk_factors_studies Límite: Humans Idioma: En Revista: MSystems Año: 2023 Tipo del documento: Article País de afiliación: China