Generation and characterization of two induced pluripotent stem cell lines from conjunctiva of a retinoblastoma patient.
Stem Cell Res
; 72: 103200, 2023 10.
Article
en En
| MEDLINE
| ID: mdl-37708614
ABSTRACT
Retinoblastoma (RB) is a common intraocular malignancy mostly caused by variation of the tumour suppressor gene RB1. In this study, we successfully generated two induced pluripotent stem cell (iPSC) lines from an infant with non-heritable RB. Both cell clones exhibited typical iPSC characteristics with normal karyotypes, consistent pluripotency markers expression and the capability of trilineage differentiation.
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Retinoblastoma
/
Neoplasias de la Retina
/
Células Madre Pluripotentes Inducidas
Límite:
Humans
/
Infant
Idioma:
En
Revista:
Stem Cell Res
Año:
2023
Tipo del documento:
Article
País de afiliación:
China