S.E.M. study of urease-induced crystalluria in the presence of hydroxamic derivatives.
Int Urol Nephrol
; 18(3): 227-33, 1986.
Article
en En
| MEDLINE
| ID: mdl-3771124
ABSTRACT
The effect of 3 hydroxamic acid derivatives on urease-induced crystalluria was studied in vitro. Acetohydroxamic acid is more effective than salicylhydroxamic and gentisohydroxamic acids in inhibiting the kinetic of urease enzymatic reaction and in retarding the formation of struvite and apatite. Crystal deposits studied by scanning electron microscope (S.E.M.) and X-ray microanalysis indicated that acetohydroxamic acid favours the formation of large crystals of struvite, and less aggregation is observed. Salicyl and gentiso derivatives favour the formation of brushite together with struvite and apatite.
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Ureasa
/
Cálculos Urinarios
/
Compuestos de Magnesio
/
Ácidos Hidroxámicos
Tipo de estudio:
Etiology_studies
Límite:
Humans
Idioma:
En
Revista:
Int Urol Nephrol
Año:
1986
Tipo del documento:
Article