Computer-aided Affinity Enhancement of a Cross-reactive Antibody against Dengue Virus Envelope Domain III.

Jonniya, Nisha Amarnath; Poddar, Sayan; Mahapatra, Subhasmita; Kar, Parimal

Jonniya, Nisha Amarnath; Poddar, Sayan; Mahapatra, Subhasmita; Kar, Parimal.

Afiliación

Jonniya NA; Department of Biosciences and Biomedical Engineering, Indian Institute of Technology Indore, Khandwa Road, Indore, 453552, Madhya Pradesh, India.
Poddar S; Department of Pharmacology, University of California San Diego, 9500 Gilman Drive, La Jolla, CA, 92093, USA.
Mahapatra S; Department of Biosciences and Biomedical Engineering, Indian Institute of Technology Indore, Khandwa Road, Indore, 453552, Madhya Pradesh, India.
Kar P; Department of Biosciences and Biomedical Engineering, Indian Institute of Technology Indore, Khandwa Road, Indore, 453552, Madhya Pradesh, India.

Cell Biochem Biophys ; 81(4): 737-755, 2023 Dec.

Article en En | MEDLINE | ID: mdl-37735329

Asunto(s)

Virus del Dengue; Dengue; Humanos; Anticuerpos Neutralizantes; Anticuerpos Antivirales; Virus del Dengue/genética; Envoltura Viral; Proteínas del Envoltorio Viral/química; Proteínas del Envoltorio Viral/genética; Dengue/prevención & control

Palabras clave

Affinity maturation; Binding energy; Computational mutagenesis; Dengue; Molecular dynamics simulations

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Dengue / Virus del Dengue Límite: Humans Idioma: En Revista: Cell Biochem Biophys Asunto de la revista: BIOFISICA / BIOQUIMICA Año: 2023 Tipo del documento: Article País de afiliación: India Pais de publicación: Estados Unidos

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