Circular RNA circARPC1B functions as a stabilisation enhancer of Vimentin to prevent high cholesterol-induced articular cartilage degeneration.

Li, Jiarui; Li, Xiang; Zhou, Shengji; Wang, Yuxin; Ying, Tiantian; Wang, Quan; Wu, Yizheng; Zhao, Fengchao

Li, Jiarui; Li, Xiang; Zhou, Shengji; Wang, Yuxin; Ying, Tiantian; Wang, Quan; Wu, Yizheng; Zhao, Fengchao.

Afiliación

Li J; Department of Orthopaedic Surgery, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China.
Li X; Department of Orthopaedic Surgery, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China.
Zhou S; Department of Orthopaedic Surgery, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China.
Wang Y; Department of Orthopaedic Surgery, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China.
Ying T; Department of Orthopaedic Surgery, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China.
Wang Q; Department of Orthopaedic Surgery, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China.
Wu Y; Department of Orthopaedic Surgery, Sir Run Run Shaw Hospital, Zhejiang University, School of Medicine, Hangzhou, China.
Zhao F; Department of Orthopaedic Surgery, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China.

Clin Transl Med ; 13(9): e1415, 2023 09.

Article en En | MEDLINE | ID: mdl-37740460

Asunto(s)

Cartílago Articular; Hipercolesterolemia; MicroARNs; Osteoartritis; Humanos; Ratones; Animales; Cartílago Articular/metabolismo; ARN Circular/metabolismo; MicroARNs/genética; Hipercolesterolemia/metabolismo; Vimentina/genética; Vimentina/metabolismo; Vimentina/farmacología; Osteoartritis/genética; Osteoartritis/tratamiento farmacológico; Osteoartritis/metabolismo; Colesterol/efectos adversos; Colesterol/metabolismo

Palabras clave

Vimentin; cholesterol; circARPC1B; osteoarthritis

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Osteoartritis / Cartílago Articular / MicroARNs / Hipercolesterolemia Tipo de estudio: Prognostic_studies Límite: Animals / Humans Idioma: En Revista: Clin Transl Med Año: 2023 Tipo del documento: Article País de afiliación: China Pais de publicación: Estados Unidos

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