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Sensitivity of Two-Tiered Lyme Disease Serology in Children With an Erythema Migrans Lesion.
Thompson, Amy D; Balamuth, Fran; Neville, Desiree N; Chapman, Laura L; Levas, Michael N; Kharbanda, Anupam B; Branda, John A; Ladell, Meagan M; Loiselle, Claire; Nigrovic, Lise E.
Afiliación
  • Thompson AD; Division of Emergency Medicine, Nemours Children's Hospital and Sidney Kimmel Medical College of Thomas Jefferson University, Wilmington, Delaware, USA.
  • Balamuth F; Department of Pediatrics, Children's Hospital of Philadelphia and University of Pennsylvania, Philadelphia, Pennsylvania, USA.
  • Neville DN; Division of Emergency Medicine, Children's Hospital of Pittsburgh and University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA.
  • Chapman LL; Division of Pediatric Emergency Medicine, Rhode Island Hospital and Warren Alpert Medical School of Brown University, Providence, Rhode Island, USA.
  • Levas MN; Department of Pediatric Emergency Medicine, Children's Hospital of Wisconsin and Medical College of Wisconsin, Milwaukee, Wisconsin, USA.
  • Kharbanda AB; Department of Emergency Medicine, Children's Minnesota, Minneapolis, Minnesota, USA.
  • Branda JA; Department of Pathology, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts, USA.
  • Ladell MM; Department of Pediatric Emergency Medicine, Children's Hospital of Wisconsin and Medical College of Wisconsin, Milwaukee, Wisconsin, USA.
  • Loiselle C; Department of Research, Nemours Children's Hospital, Wilmington, Delaware, USA.
  • Nigrovic LE; Division of Emergency Medicine, Boston Children's Hospital and Harvard Medical School, Boston, Massachusetts, USA.
J Pediatric Infect Dis Soc ; 12(10): 553-555, 2023 Oct 28.
Article en En | MEDLINE | ID: mdl-37756491
ABSTRACT
In our prospective cohort of 192 children with a physician-diagnosed erythema migrans (EM) lesion, two-tier Lyme disease serology had higher sensitivity in children with multiple EM lesions (76.8% multiple lesions vs. 38.1% single EM; difference 38.7%, 95% confidence interval 24.8%-50.4%). The diagnosis of cutaneous Lyme disease should be based on careful physical examination rather than laboratory testing.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Enfermedad de Lyme / Eritema Crónico Migrans Tipo de estudio: Diagnostic_studies Límite: Child / Humans Idioma: En Revista: J Pediatric Infect Dis Soc Año: 2023 Tipo del documento: Article País de afiliación: Estados Unidos
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Enfermedad de Lyme / Eritema Crónico Migrans Tipo de estudio: Diagnostic_studies Límite: Child / Humans Idioma: En Revista: J Pediatric Infect Dis Soc Año: 2023 Tipo del documento: Article País de afiliación: Estados Unidos