Celecoxib-Loaded Self-micellizing Solid Dispersion Suppresses Its Delayed Absorption in Rats with Impaired Gastrointestinal Motility.

Ogino, Mizuki; Yakushiji, Keisuke; Suzuki, Hiroki; Yamauchi, Yukinori; Seto, Yoshiki; Sato, Hideyuki; Onoue, Satomi

Ogino, Mizuki; Yakushiji, Keisuke; Suzuki, Hiroki; Yamauchi, Yukinori; Seto, Yoshiki; Sato, Hideyuki; Onoue, Satomi.

Afiliación

Ogino M; Laboratory of Biopharmacy, School of Pharmaceutical Sciences, University of Shizuoka.
Yakushiji K; Laboratory of Biopharmacy, School of Pharmaceutical Sciences, University of Shizuoka.
Suzuki H; Laboratory of Biopharmacy, School of Pharmaceutical Sciences, University of Shizuoka.
Yamauchi Y; Department of Pharmaceutical Physical Chemistry, College of Pharmaceutical Sciences, Matsuyama University.
Seto Y; Laboratory of Biopharmacy, School of Pharmaceutical Sciences, University of Shizuoka.
Sato H; Laboratory of Biopharmacy, School of Pharmaceutical Sciences, University of Shizuoka.
Onoue S; Laboratory of Biopharmacy, School of Pharmaceutical Sciences, University of Shizuoka.

Chem Pharm Bull (Tokyo) ; 71(10): 787-791, 2023.

Article en En | MEDLINE | ID: mdl-37779081

Asunto(s)

Motilidad Gastrointestinal; Micelas; Ratas; Animales; Celecoxib/farmacología; Ratas Sprague-Dawley; Solubilidad; Dolor

Palabras clave

celecoxib; oral absorption; pharmacokinetic alteration; self-micellizing solid dispersion

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Motilidad Gastrointestinal / Micelas Tipo de estudio: Prognostic_studies Límite: Animals Idioma: En Revista: Chem Pharm Bull (Tokyo) Año: 2023 Tipo del documento: Article Pais de publicación: Japón

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