Ubiquitination of ASCL1 mediates CD47 transcriptional activation of the AKT signaling pathway, and glycolysis promotes osteogenic differentiation of hBMSCs.

Zhang, Jimei; Zhu, Ling; Zhou, Jianping; Yu, Qunying; Yang, Guangyuan; Zhao, Ke; Luo, Chaoli; Meng, Jianguo; Liu, Jing; Yang, Xuming

Zhang, Jimei; Zhu, Ling; Zhou, Jianping; Yu, Qunying; Yang, Guangyuan; Zhao, Ke; Luo, Chaoli; Meng, Jianguo; Liu, Jing; Yang, Xuming.

Afiliación

Zhang J; Department of Gastroenterology, Chenggong Hospital, Yan an Hospital Affiliated to Kunming Medical University, Kunming, 650505, China.
Zhu L; Department of Orthopedics, Chenggong Hospital, Yan an Hospital Affiliated to Kunming Medical University, Kunming, 650505, China.
Zhou J; Department of Orthopedics, Chenggong Hospital, Yan an Hospital Affiliated to Kunming Medical University, Kunming, 650505, China.
Yu Q; Department of Obstetrics, The Second Affiliated Hospital of Kunming Medical University, Kunming, 650101, China.
Yang G; Kunming Medical University, Kunming, 650500, China.
Zhao K; Department of Orthopedics, Yunnan Pain Disease Hospital, Kunming, 650224, China.
Luo C; Operating Room, Yunnan Pain Disease Hospital, Kunming, 650224, China.
Meng J; Department of Orthopedics, Guangnan Hospital of Traditional Chinese Medicine, Yunnan Province, Guangnan, 663300, China.
Liu J; Department of Orthopedics, Chenggong Hospital, Yan an Hospital Affiliated to Kunming Medical University, Kunming, 650505, China.
Yang X; Department of Orthopedics, Yan an Hospital Affiliated to Kunming Medical University, Kunming, 650055, China. yangxmkm@163.com.

In Vitro Cell Dev Biol Anim ; 59(8): 636-648, 2023 Sep.

Article en En | MEDLINE | ID: mdl-37783914

Asunto(s)

MicroARNs; Osteogénesis; Animales; Antígeno CD47/genética; Antígeno CD47/metabolismo; Diferenciación Celular/genética; Células Cultivadas; MicroARNs/genética; Osteogénesis/genética; Proteínas Proto-Oncogénicas c-akt/metabolismo; Transducción de Señal; Activación Transcripcional

Palabras clave

ASCL1; CD47; Glycolysis; Ubiquitination; hBMSC osteogenic differentiation

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Osteogénesis / MicroARNs Límite: Animals Idioma: En Revista: In Vitro Cell Dev Biol Anim Asunto de la revista: BIOLOGIA Año: 2023 Tipo del documento: Article País de afiliación: China Pais de publicación: Alemania

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