Treatment of primary cancer in metastatic hormone-sensitive prostate cancer.
Curr Opin Support Palliat Care
; 17(4): 315-323, 2023 12 01.
Article
en En
| MEDLINE
| ID: mdl-37788147
ABSTRACT
PURPOSE OF REVIEW Recently, there has been emerging interest in the treatment of primary tumours in metastatic prostate cancer based on major trials that have provided evidence for radiation therapy and cytoreductive radical prostatectomy. Preclinical studies have further established the molecular features of metastatic disease that provide a rationale for primary treatment. RECENT FINDINGS:
Several randomised controlled trials and other prospective studies have demonstrated a benefit in overall survival, predominantly in low-volume disease. Advancements in precision medicine also offer insight into improving selection, staging and monitoring.SUMMARY:
In this review, the authors highlight and review recent data on emerging and established treatment options and shift towards personalised medicine for hormone-sensitive metastatic prostate cancer.
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Neoplasias de la Próstata
Tipo de estudio:
Clinical_trials
/
Diagnostic_studies
/
Observational_studies
Límite:
Humans
/
Male
Idioma:
En
Revista:
Curr Opin Support Palliat Care
Año:
2023
Tipo del documento:
Article