Cervical cell's nucleus segmentation through an improved UNet architecture.
PLoS One
; 18(10): e0283568, 2023.
Article
en En
| MEDLINE
| ID: mdl-37788295
ABSTRACT
Precise segmentation of the nucleus is vital for computer-aided diagnosis (CAD) in cervical cytology. Automated delineation of the cervical nucleus has notorious challenges due to clumped cells, color variation, noise, and fuzzy boundaries. Due to its standout performance in medical image analysis, deep learning has gained attention from other techniques. We have proposed a deep learning model, namely C-UNet (Cervical-UNet), to segment cervical nuclei from overlapped, fuzzy, and blurred cervical cell smear images. Cross-scale features integration based on a bi-directional feature pyramid network (BiFPN) and wide context unit are used in the encoder of classic UNet architecture to learn spatial and local features. The decoder of the improved network has two inter-connected decoders that mutually optimize and integrate these features to produce segmentation masks. Each component of the proposed C-UNet is extensively evaluated to judge its effectiveness on a complex cervical cell dataset. Different data augmentation techniques were employed to enhance the proposed model's training. Experimental results have shown that the proposed model outperformed extant models, i.e., CGAN (Conditional Generative Adversarial Network), DeepLabv3, Mask-RCNN (Region-Based Convolutional Neural Network), and FCN (Fully Connected Network), on the employed dataset used in this study and ISBI-2014 (International Symposium on Biomedical Imaging 2014), ISBI-2015 datasets. The C-UNet achieved an object-level accuracy of 93%, pixel-level accuracy of 92.56%, object-level recall of 95.32%, pixel-level recall of 92.27%, Dice coefficient of 93.12%, and F1-score of 94.96% on complex cervical images dataset.
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Procesamiento de Imagen Asistido por Computador
/
Redes Neurales de la Computación
Tipo de estudio:
Diagnostic_studies
/
Prognostic_studies
Límite:
Female
/
Humans
Idioma:
En
Revista:
PLoS One
Asunto de la revista:
CIENCIA
/
MEDICINA
Año:
2023
Tipo del documento:
Article
País de afiliación:
Pakistán