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Device-Measured Physical Activity and Sedentary Behavior in Relation to Cardiovascular Diseases and All-Cause Mortality: Systematic Review and Meta-Analysis of Prospective Cohort Studies.
Liew, Seaw Jia; Petrunoff, Nicholas A; Neelakantan, Nithya; van Dam, Rob M; Müller-Riemenschneider, Falk.
Afiliación
  • Liew SJ; Saw Swee Hock School of Public Health, National University of Singapore and National University Health System, Singapore.
  • Petrunoff NA; Yong Loo Lin School of Medicine, National University of Singapore and National University Health System, Singapore.
  • Neelakantan N; Saw Swee Hock School of Public Health, National University of Singapore and National University Health System, Singapore.
  • van Dam RM; Saw Swee Hock School of Public Health, National University of Singapore and National University Health System, Singapore.
  • Müller-Riemenschneider F; Saw Swee Hock School of Public Health, National University of Singapore and National University Health System, Singapore.
AJPM Focus ; 2(1): 100054, 2023 Mar.
Article en En | MEDLINE | ID: mdl-37789935
ABSTRACT

Introduction:

This review synthesized evidence from prospective cohort studies on the association of device-measured physical activity and sedentary behavior with cardiovascular disease and all-cause mortality among adults.

Methods:

Five databases were searched from 2000 through April 29, 2020. Study quality was appraised using the NIH Quality Assessment Tool. Pooled hazard ratio and 95% CI were obtained from random-effects meta-analyses. Subgroup analyses by age and sex were conducted for studies on all-cause mortality.

Results:

Of 29 articles included in the systematic review, 5 studies on cardiovascular disease mortality and 15 studies on all-cause mortality were included in meta-analyses. Comparing the highest with the lowest exposure categories, the pooled hazard ratios (95% CIs) for cardiovascular disease mortality were 0.29 (CI=0.18, 0.47) for total physical activity, 0.37 (CI=0.25, 0.55) for moderate-to-vigorous physical activity, 0.62 (0.41-0.93) for light physical activity, and 1.89 (CI=1.09, 3.29) for sedentary behavior. The pooled hazard ratios (95% CIs) for all-cause mortality were 0.42 (CI=0.34, 0.53) for total physical activity, 0.43 (CI=0.35, 0.53) for moderate-to-vigorous physical activity, 0.58 (CI=0.43, 0.80) for light physical activity, and 1.58 (CI=1.19, 2.09) for sedentary behavior. The pooled hazard ratio (95% CI) for all-cause mortality was 0.35 (CI=0.29, 0.42) for steps per day, but the studies available for analysis were conducted in older adults. The results of subgroup analyses were consistent with the main results.

Discussion:

Rapidly accumulating evidence suggests that more physical activity and less sedentary behavior are associated with a lower risk of cardiovascular disease and all-cause mortality. Similar beneficial relationships were found for step counts and all-cause mortality among older adults. Future studies employing standardized research methodologies and up-to-date data processing approaches are warranted to recommend specific amounts of physical activity and limits to sedentary behavior.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Tipo de estudio: Etiology_studies / Observational_studies / Risk_factors_studies / Systematic_reviews Idioma: En Revista: AJPM Focus Año: 2023 Tipo del documento: Article País de afiliación: Singapur

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Tipo de estudio: Etiology_studies / Observational_studies / Risk_factors_studies / Systematic_reviews Idioma: En Revista: AJPM Focus Año: 2023 Tipo del documento: Article País de afiliación: Singapur