Improved computational epitope profiling using structural models identifies a broader diversity of antibodies that bind to the same epitope.

Spoendlin, Fabian C; Abanades, Brennan; Raybould, Matthew I J; Wong, Wing Ki; Georges, Guy; Deane, Charlotte M

Spoendlin, Fabian C; Abanades, Brennan; Raybould, Matthew I J; Wong, Wing Ki; Georges, Guy; Deane, Charlotte M.

Afiliación

Spoendlin FC; Oxford Protein Informatics Group, Department of Statistics, University of Oxford, Oxford, United Kingdom.
Abanades B; Oxford Protein Informatics Group, Department of Statistics, University of Oxford, Oxford, United Kingdom.
Raybould MIJ; Oxford Protein Informatics Group, Department of Statistics, University of Oxford, Oxford, United Kingdom.
Wong WK; Large Molecule Research, Roche Pharma Research and Early Development, Roche Innovation Center Munich, Penzberg, Germany.
Georges G; Large Molecule Research, Roche Pharma Research and Early Development, Roche Innovation Center Munich, Penzberg, Germany.
Deane CM; Oxford Protein Informatics Group, Department of Statistics, University of Oxford, Oxford, United Kingdom.

Front Mol Biosci ; 10: 1237621, 2023.

Article en En | MEDLINE | ID: mdl-37790877

Palabras clave

antibody; clonotyping; clustering; epitope; epitope profiling; structure prediction

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Tipo de estudio: Prognostic_studies Idioma: En Revista: Front Mol Biosci Año: 2023 Tipo del documento: Article País de afiliación: Reino Unido Pais de publicación: Suiza

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