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Plasma proteomic associations with genetics and health in the UK Biobank.
Sun, Benjamin B; Chiou, Joshua; Traylor, Matthew; Benner, Christian; Hsu, Yi-Hsiang; Richardson, Tom G; Surendran, Praveen; Mahajan, Anubha; Robins, Chloe; Vasquez-Grinnell, Steven G; Hou, Liping; Kvikstad, Erika M; Burren, Oliver S; Davitte, Jonathan; Ferber, Kyle L; Gillies, Christopher E; Hedman, Åsa K; Hu, Sile; Lin, Tinchi; Mikkilineni, Rajesh; Pendergrass, Rion K; Pickering, Corran; Prins, Bram; Baird, Denis; Chen, Chia-Yen; Ward, Lucas D; Deaton, Aimee M; Welsh, Samantha; Willis, Carissa M; Lehner, Nick; Arnold, Matthias; Wörheide, Maria A; Suhre, Karsten; Kastenmüller, Gabi; Sethi, Anurag; Cule, Madeleine; Raj, Anil; Burkitt-Gray, Lucy; Melamud, Eugene; Black, Mary Helen; Fauman, Eric B; Howson, Joanna M M; Kang, Hyun Min; McCarthy, Mark I; Nioi, Paul; Petrovski, Slavé; Scott, Robert A; Smith, Erin N; Szalma, Sándor; Waterworth, Dawn M.
Afiliación
  • Sun BB; Translational Sciences, Research & Development, Biogen, Cambridge, MA, USA. bbsun92@outlook.com.
  • Chiou J; Internal Medicine Research Unit, Worldwide Research, Development and Medical, Pfizer, Cambridge, MA, USA.
  • Traylor M; Human Genetics Centre of Excellence, Novo Nordisk Research Centre Oxford, Oxford, UK.
  • Benner C; Genentech, San Francisco, CA, USA.
  • Hsu YH; Amgen Research, Cambridge, MA, USA.
  • Richardson TG; Human Genetics Centre of Excellence, Novo Nordisk Research Centre Oxford, Oxford, UK.
  • Surendran P; Genomic Sciences, GlaxoSmithKline, Stevenage, UK.
  • Mahajan A; Genomic Sciences, GlaxoSmithKline, Stevenage, UK.
  • Robins C; Genentech, San Francisco, CA, USA.
  • Vasquez-Grinnell SG; Genomic Sciences, GlaxoSmithKline, Collegeville, PA, USA.
  • Hou L; Bristol Myers Squibb, Princeton, NJ, USA.
  • Kvikstad EM; Population Analytics, Janssen Research & Development, Spring House, PA, USA.
  • Burren OS; Bristol Myers Squibb, Princeton, NJ, USA.
  • Davitte J; Centre for Genomics Research, Discovery Sciences, BioPharmaceuticals R&D, AstraZeneca, Cambridge, UK.
  • Ferber KL; Genomic Sciences, GlaxoSmithKline, Collegeville, PA, USA.
  • Gillies CE; Biostatistics, Research and Development, Biogen, Cambridge, MA, USA.
  • Hedman ÅK; Regeneron Genetics Center, Tarrytown, NY, USA.
  • Hu S; External Science and Innovation Target Sciences, Worldwide Research, Development and Medical, Pfizer, Stockholm, Sweden.
  • Lin T; Human Genetics Centre of Excellence, Novo Nordisk Research Centre Oxford, Oxford, UK.
  • Mikkilineni R; Analytics and Data Sciences, Biogen, Cambridge, MA, USA.
  • Pendergrass RK; Data Science Institute, Takeda Development Center Americas, Cambridge, MA, USA.
  • Pickering C; Genentech, San Francisco, CA, USA.
  • Prins B; UK Biobank, Stockport, UK.
  • Baird D; Centre for Genomics Research, Discovery Sciences, BioPharmaceuticals R&D, AstraZeneca, Cambridge, UK.
  • Chen CY; Translational Sciences, Research & Development, Biogen, Cambridge, MA, USA.
  • Ward LD; Translational Sciences, Research & Development, Biogen, Cambridge, MA, USA.
  • Deaton AM; Alnylam Human Genetics, Discovery & Translational Research, Alnylam Pharmaceuticals, Cambridge, MA, USA.
  • Welsh S; Alnylam Human Genetics, Discovery & Translational Research, Alnylam Pharmaceuticals, Cambridge, MA, USA.
  • Willis CM; UK Biobank, Stockport, UK.
  • Lehner N; Alnylam Human Genetics, Discovery & Translational Research, Alnylam Pharmaceuticals, Cambridge, MA, USA.
  • Arnold M; Institute of Computational Biology, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany.
  • Wörheide MA; Institute of Computational Biology, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany.
  • Suhre K; Department of Psychiatry and Behavioral Sciences, Duke University, Durham, NC, USA.
  • Kastenmüller G; Institute of Computational Biology, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany.
  • Sethi A; Bioinformatics Core, Weill Cornell Medicine-Qatar, Doha, Qatar.
  • Cule M; Institute of Computational Biology, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany.
  • Raj A; Calico Life Sciences, San Francisco, CA, USA.
  • Black MH; UK Biobank, Stockport, UK.
  • Fauman EB; Calico Life Sciences, San Francisco, CA, USA.
  • Howson JMM; Population Analytics, Janssen Research & Development, Spring House, PA, USA.
  • Kang HM; Internal Medicine Research Unit, Worldwide Research, Development and Medical, Pfizer, Cambridge, MA, USA.
  • McCarthy MI; Human Genetics Centre of Excellence, Novo Nordisk Research Centre Oxford, Oxford, UK.
  • Nioi P; Regeneron Genetics Center, Tarrytown, NY, USA.
  • Petrovski S; Genentech, San Francisco, CA, USA.
  • Scott RA; Alnylam Human Genetics, Discovery & Translational Research, Alnylam Pharmaceuticals, Cambridge, MA, USA.
  • Smith EN; Centre for Genomics Research, Discovery Sciences, BioPharmaceuticals R&D, AstraZeneca, Cambridge, UK.
  • Szalma S; Department of Medicine, University of Melbourne, Austin Health, Melbourne, Victoria, Australia.
  • Waterworth DM; Genomic Sciences, GlaxoSmithKline, Stevenage, UK.
Nature ; 622(7982): 329-338, 2023 Oct.
Article en En | MEDLINE | ID: mdl-37794186
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Proteínas Sanguíneas / Salud / Bases de Datos Factuales / Bancos de Muestras Biológicas / Proteoma / Genómica / Proteómica Tipo de estudio: Prognostic_studies / Risk_factors_studies Límite: Humans País/Región como asunto: Europa Idioma: En Revista: Nature Año: 2023 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Reino Unido
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Proteínas Sanguíneas / Salud / Bases de Datos Factuales / Bancos de Muestras Biológicas / Proteoma / Genómica / Proteómica Tipo de estudio: Prognostic_studies / Risk_factors_studies Límite: Humans País/Región como asunto: Europa Idioma: En Revista: Nature Año: 2023 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Reino Unido