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Inactive S. aureus Cas9 downregulates alpha-synuclein and reduces mtDNA damage and oxidative stress levels in human stem cell model of Parkinson's disease.
Sastre, Danuta; Zafar, Faria; Torres, C Alejandra Morato; Piper, Desiree; Kirik, Deniz; Sanders, Laurie H; Qi, L Stanley; Schüle, Birgitt.
Afiliación
  • Sastre D; Department of Pathology, Stanford University School of Medicine, 300 Pasteur Dr., R271/217, Stanford, CA, 94305, USA.
  • Zafar F; Department of Pathology, Stanford University School of Medicine, 300 Pasteur Dr., R271/217, Stanford, CA, 94305, USA.
  • Torres CAM; Department of Pathology, Stanford University School of Medicine, 300 Pasteur Dr., R271/217, Stanford, CA, 94305, USA.
  • Piper D; Department of Biological Sciences, San Jose State University, San Jose, CA, 95192, USA.
  • Kirik D; Department of Experimental Medical Science, Lund University, Lund, Sweden.
  • Sanders LH; Departments of Neurology and Pathology, Duke Center for Neurodegeneration and Neurotherapeutics, Duke University Medical Center, Durham, NC, 27710, USA.
  • Qi LS; Department of Bioengineering, Stanford University, Stanford, CA, 94305, USA.
  • Schüle B; Department of Pathology, Stanford University School of Medicine, 300 Pasteur Dr., R271/217, Stanford, CA, 94305, USA. bschuele@stanford.edu.
Sci Rep ; 13(1): 17796, 2023 10 18.
Article en En | MEDLINE | ID: mdl-37853101
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Enfermedad de Parkinson / Staphylococcus aureus Resistente a Meticilina Límite: Humans Idioma: En Revista: Sci Rep Año: 2023 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Reino Unido
Texto completo
Añadir a Mi BVS
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XML
PubMed Links
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Enfermedad de Parkinson / Staphylococcus aureus Resistente a Meticilina Límite: Humans Idioma: En Revista: Sci Rep Año: 2023 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Reino Unido