ROCK1 activates mitochondrial fission leading to oxidative stress and muscle atrophy.

Si, Meijun; Yu, Rizhen; Lin, Hongchun; Li, Feng; Jung, Sungyun; Thomas, Sandhya S; Danesh, Farhard S; Wang, Yanlin; Peng, Hui; Hu, Zhaoyong

Si, Meijun; Yu, Rizhen; Lin, Hongchun; Li, Feng; Jung, Sungyun; Thomas, Sandhya S; Danesh, Farhard S; Wang, Yanlin; Peng, Hui; Hu, Zhaoyong.

Afiliación

Si M; Nephrology Division, Third Affiliated Hospital of Sun Yat-sen University, Guangzhou, China.
Yu R; Department of Nephrology, Guangdong Provincial People's Hospital, Guangdong Academy of Medical Sciences; Guangzhou, China.
Lin H; Nephrology Division, Department of Medicine, Baylor College of Medicine, Houston, Texas, USA.
Li F; Nephrology Division, Zhejiang Provincial People's Hospital, People's Hospital of Hangzhou Medical College, Hangzhou, Hangzhou, Zhejiang, China.
Jung S; Nephrology Division, Department of Medicine, Baylor College of Medicine, Houston, Texas, USA.
Thomas SS; Nephrology Division, Third Affiliated Hospital of Sun Yat-sen University, Guangzhou, China.
Danesh FS; Nephrology Division, Department of Medicine, Baylor College of Medicine, Houston, Texas, USA.
Wang Y; Department of Biochemistry and Molecular Biology, Baylor College of Medicine, Houston, Texas, USA.
Peng H; Department of Biochemistry and Molecular Biology, Baylor College of Medicine, Houston, Texas, USA.
Hu Z; Nephrology Division, Department of Medicine, Baylor College of Medicine, Houston, Texas, USA.

bioRxiv ; 2023 Oct 22.

Article en En | MEDLINE | ID: mdl-37905139

Palabras clave

Muscle atrophy; ROS; chronic kidney disease; mitochondrial fission; oxidative stress

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: BioRxiv Año: 2023 Tipo del documento: Article País de afiliación: China Pais de publicación: Estados Unidos

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