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Extensive systemic thrombo-embolism including intra-cardiac thrombosis mimicking an atrial myxoma in a patient with beta thalassaemia major - a case report.
Welhenge, Chiranthi; Ranasinghe, Rumesh; Rajapakse, Sanjeewa; Premawardhena, Anuja.
Afiliación
  • Welhenge C; University Medical Unit, North Colombo (Teaching) Hospital, Ragama, Sri Lanka. chiranthi_welhenge@yahoo.com.
  • Ranasinghe R; University Medical Unit, North Colombo (Teaching) Hospital, Ragama, Sri Lanka.
  • Rajapakse S; Cardiology Unit, North Colombo (Teaching) Hospital, Ragama, Sri Lanka.
  • Premawardhena A; Department of Medicine, Faculty of Medicine, University of Kelaniya, Ragama, Sri Lanka.
BMC Cardiovasc Disord ; 23(1): 532, 2023 10 31.
Article en En | MEDLINE | ID: mdl-37907862
BACKGROUND: Sepsis and thrombo-embolic disease are well known complications of thalassemia major. Intracardiac thrombi are however rare and can lead to diagnostic dilemmas. CASE PRESENTATION: We report the case of a 20-year-old female splenectomised thalassaemia major patient with severe iron overload, who presented with life threatening sepsis associated with a liver abscess. Discovery of a large oscillating intra cardiac lesion on 2D echocardiogram confirmed by Contrast Enhanced Computed Tomography (CECT) chest in the right atrium extending from the left hepatic vein through the inferior vena cava complicated the clinical course. After a prolonged Intensive Care Unit (ICU) stay supported with antibiotics and anticoagulation, she recovered with evidence of resolution of the intra cardiac thrombus. CONCLUSIONS: Early recognition and prompt aggressive treatment of sepsis in patients with thalassemia is essential to prevent complications. Intracardiac thrombosis is a potentially treatable cause for an intra cardiac mass in patients with thalassemia major, which should not be missed.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Fibrilación Atrial / Trombosis / Talasemia beta / Sepsis / Embolia / Cardiopatías / Neoplasias Cardíacas / Mixoma Límite: Adult / Female / Humans Idioma: En Revista: BMC Cardiovasc Disord Asunto de la revista: ANGIOLOGIA / CARDIOLOGIA Año: 2023 Tipo del documento: Article País de afiliación: Sri Lanka Pais de publicación: Reino Unido

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Fibrilación Atrial / Trombosis / Talasemia beta / Sepsis / Embolia / Cardiopatías / Neoplasias Cardíacas / Mixoma Límite: Adult / Female / Humans Idioma: En Revista: BMC Cardiovasc Disord Asunto de la revista: ANGIOLOGIA / CARDIOLOGIA Año: 2023 Tipo del documento: Article País de afiliación: Sri Lanka Pais de publicación: Reino Unido