Targeting the SARS-CoV-2 RNA-dependent RNA polymerase (RdRp) with synthetic/designer unnatural nucleoside analogs: an in silico study.

Bag, Subhendu Sekhar; Sinha, Sayantan; Dutta, Soumya; Baishya, Hirak Jyoti; Paul, Suravi

Bag, Subhendu Sekhar; Sinha, Sayantan; Dutta, Soumya; Baishya, Hirak Jyoti; Paul, Suravi.

Afiliación

Bag SS; Chemical Biology/Genomics Laboratory, Department of Chemistry, Indian Institute of Technology Guwahati, Guwahati, Assam, India, 781039. ssbag75@iitg.ac.in.
Sinha S; Centre for the Environment, Indian Institute of Technology Guwahati, Guwahati, Assam, India, 781039. ssbag75@iitg.ac.in.
Dutta S; Centre for the Environment, Indian Institute of Technology Guwahati, Guwahati, Assam, India, 781039.
Baishya HJ; Chemical Biology/Genomics Laboratory, Department of Chemistry, Indian Institute of Technology Guwahati, Guwahati, Assam, India, 781039.
Paul S; Chemical Biology/Genomics Laboratory, Department of Chemistry, Indian Institute of Technology Guwahati, Guwahati, Assam, India, 781039.

J Mol Model ; 29(12): 366, 2023 Nov 11.

Article en En | MEDLINE | ID: mdl-37950101

Asunto(s)

COVID-19; Nucleósidos; Antivirales/farmacología; Simulación del Acoplamiento Molecular; Simulación de Dinámica Molecular; Nucleósidos/farmacología; ARN Viral; ARN Polimerasa Dependiente del ARN; SARS-CoV-2

Palabras clave

ADMET; COVID-19; Designer nucleosides; Molecular docking; Molecular dynamics; SARS-CoV-2 RdRp; Unnatural nucleoside

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: COVID-19 / Nucleósidos Idioma: En Revista: J Mol Model Asunto de la revista: BIOLOGIA MOLECULAR Año: 2023 Tipo del documento: Article Pais de publicación: Alemania

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