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Single-cell analysis of memory B cells from top neutralizers reveals multiple sites of vulnerability within HCMV Trimer and Pentamer.
Zehner, Matthias; Alt, Mira; Ashurov, Artem; Goldsmith, Jory A; Spies, Rebecca; Weiler, Nina; Lerma, Justin; Gieselmann, Lutz; Stöhr, Dagmar; Gruell, Henning; Schultz, Eric P; Kreer, Christoph; Schlachter, Linda; Janicki, Hanna; Laib Sampaio, Kerstin; Stegmann, Cora; Nemetchek, Michelle D; Dähling, Sabrina; Ullrich, Leon; Dittmer, Ulf; Witzke, Oliver; Koch, Manuel; Ryckman, Brent J; Lotfi, Ramin; McLellan, Jason S; Krawczyk, Adalbert; Sinzger, Christian; Klein, Florian.
Afiliación
  • Zehner M; Laboratory of Experimental Immunology, Institute of Virology, Faculty of Medicine and University Hospital Cologne, University of Cologne, 50931 Cologne, Germany. Electronic address: matthias.zehner@uk-koeln.de.
  • Alt M; Department of Infectious Diseases, West German Centre of Infectious Diseases, University Hospital Essen, University Duisburg-Essen, 45147 Essen, Germany.
  • Ashurov A; Laboratory of Experimental Immunology, Institute of Virology, Faculty of Medicine and University Hospital Cologne, University of Cologne, 50931 Cologne, Germany.
  • Goldsmith JA; Department of Molecular Biosciences, The University of Texas at Austin, Austin, TX 78712, USA.
  • Spies R; Institute for Virology, Ulm University Medical Center, 89081 Ulm, Germany.
  • Weiler N; Institute for Virology, Ulm University Medical Center, 89081 Ulm, Germany.
  • Lerma J; Department of Molecular Biosciences, The University of Texas at Austin, Austin, TX 78712, USA.
  • Gieselmann L; Laboratory of Experimental Immunology, Institute of Virology, Faculty of Medicine and University Hospital Cologne, University of Cologne, 50931 Cologne, Germany; German Center for Infection Research, Partner Site Bonn-Cologne, 50931 Cologne, Germany.
  • Stöhr D; Institute for Virology, Ulm University Medical Center, 89081 Ulm, Germany.
  • Gruell H; Laboratory of Experimental Immunology, Institute of Virology, Faculty of Medicine and University Hospital Cologne, University of Cologne, 50931 Cologne, Germany.
  • Schultz EP; Division of Biological Sciences, University of Montana, Missoula, MT 59812, USA; Center for Biomolecular Structure and Dynamics, University of Montana, Missoula, MT 59812, USA.
  • Kreer C; Laboratory of Experimental Immunology, Institute of Virology, Faculty of Medicine and University Hospital Cologne, University of Cologne, 50931 Cologne, Germany.
  • Schlachter L; Laboratory of Experimental Immunology, Institute of Virology, Faculty of Medicine and University Hospital Cologne, University of Cologne, 50931 Cologne, Germany.
  • Janicki H; Laboratory of Experimental Immunology, Institute of Virology, Faculty of Medicine and University Hospital Cologne, University of Cologne, 50931 Cologne, Germany.
  • Laib Sampaio K; Institute for Virology, Ulm University Medical Center, 89081 Ulm, Germany.
  • Stegmann C; Division of Biological Sciences, University of Montana, Missoula, MT 59812, USA; Center for Biomolecular Structure and Dynamics, University of Montana, Missoula, MT 59812, USA.
  • Nemetchek MD; Division of Biological Sciences, University of Montana, Missoula, MT 59812, USA; Center for Biomolecular Structure and Dynamics, University of Montana, Missoula, MT 59812, USA.
  • Dähling S; Laboratory of Experimental Immunology, Institute of Virology, Faculty of Medicine and University Hospital Cologne, University of Cologne, 50931 Cologne, Germany.
  • Ullrich L; Laboratory of Experimental Immunology, Institute of Virology, Faculty of Medicine and University Hospital Cologne, University of Cologne, 50931 Cologne, Germany.
  • Dittmer U; Institute for Virology, University Hospital Essen, University of Duisburg-Essen, 45147 Essen, Germany.
  • Witzke O; Department of Infectious Diseases, West German Centre of Infectious Diseases, University Hospital Essen, University Duisburg-Essen, 45147 Essen, Germany.
  • Koch M; Institute for Dental Research and Oral Musculoskeletal Biology, Center for Biochemistry, Faculty of Medicine and University Hospital Cologne, University of Cologne, 50931 Cologne, Germany.
  • Ryckman BJ; Division of Biological Sciences, University of Montana, Missoula, MT 59812, USA; Center for Biomolecular Structure and Dynamics, University of Montana, Missoula, MT 59812, USA.
  • Lotfi R; Institute for Transfusion Medicine, Ulm University Medical Center, 89081 Ulm, Germany.
  • McLellan JS; Department of Molecular Biosciences, The University of Texas at Austin, Austin, TX 78712, USA.
  • Krawczyk A; Department of Infectious Diseases, West German Centre of Infectious Diseases, University Hospital Essen, University Duisburg-Essen, 45147 Essen, Germany; Institute for Virology, University Hospital Essen, University of Duisburg-Essen, 45147 Essen, Germany.
  • Sinzger C; Institute for Virology, Ulm University Medical Center, 89081 Ulm, Germany.
  • Klein F; Laboratory of Experimental Immunology, Institute of Virology, Faculty of Medicine and University Hospital Cologne, University of Cologne, 50931 Cologne, Germany; German Center for Infection Research, Partner Site Bonn-Cologne, 50931 Cologne, Germany; Center for Molecular Medicine Cologne (CMMC), Uni
Immunity ; 56(11): 2602-2620.e10, 2023 Nov 14.
Article en En | MEDLINE | ID: mdl-37967532
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Proteínas del Envoltorio Viral / Citomegalovirus Límite: Humans / Newborn Idioma: En Revista: Immunity Asunto de la revista: ALERGIA E IMUNOLOGIA Año: 2023 Tipo del documento: Article Pais de publicación: Estados Unidos
Texto completo
Añadir a Mi BVS
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XML
PubMed Links
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Proteínas del Envoltorio Viral / Citomegalovirus Límite: Humans / Newborn Idioma: En Revista: Immunity Asunto de la revista: ALERGIA E IMUNOLOGIA Año: 2023 Tipo del documento: Article Pais de publicación: Estados Unidos